The 6 Best Boutique Hotels with Spa in Wine Route Mendoza (2025)

Nestled in the foothills of the Andes, the Wine Route Mendoza boasts a sun-drenched landscape dotted with sprawling vineyards and rustic bodegas that celebrate Argentina's rich viticultural heritage. The region pulses with life, its vibrant culinary scene offering everything from traditional asados to gourmet wine pairings, while charming towns exude a warm, inviting atmosphere that beckons exploration. Here, boutique hotels embody the essence of this enchanting destination, providing not only luxurious accommodations but also an intimate connection to the local culture. Casa de Uco Vineyards and Wine Resort stands out for its stunning architecture and panoramic vineyard views, making it a haven for wine enthusiasts. Meanwhile, Casa de Huéspedes Bodega Gimenez Riili enchants with its personalized service and cozy ambiance, situated right amidst the vines. Club Tapiz offers a unique blend of contemporary style and historical charm, perfect for those seeking both relaxation and adventure. Discover the allure of Wine Route Mendoza boutique hotels with spa services, and let us guide you in planning an unforgettable getaway amidst the vineyards.

List Of Best Boutique Hotels with Spa Wine Route Mendoza

boutique hotels in Wine Route Mendoza

Casa de Uco Vineyards and Wine Resort

Hotel
Ruta Provincial 94 km 14,5, 5565 Los Árboles, Argentina

Nestled amidst the rolling vineyards of Los Árboles, Casa de Uco Vineyards and Wine Resort offers a luxurious escape where romance meets adventure. Here, every moment is infused with the beauty of your surroundings—from spectacular mountain vistas to fragrant gardens—creating an intimate oasis perfect for discerning travelers seeking solace and inspiration in Argentina’s renowned wine country.

Romantic Retreat - Indulge in elegantly designed guest rooms, where modern comforts meet the warmth of rustic charm. Witness breathtaking sunsets over endless rows of vines from your private balcony, creating a picturesque backdrop for cherished memories.

Culinary Delights - Savor a fusion of international and regional cuisine at Restaurant Bistreaux, where every dish is crafted with fresh, local ingredients. From the rich aromas of freshly prepared empanadas to the elegant presentation of delectable wines, dining here is an experience that tantalizes all your senses.

Wellness & Nature - Unwind at the spa with treatments inspired by the natural bounty around you or embark on a serene horseback ride through the stunning landscape. The rhythmic sounds of nature accompany your adventures, ensuring that relaxation and rejuvenation are never out of reach.

Guest Experiences - As guests wander the sprawling grounds, they often stumble upon delightful surprises—a hand-written note left by the staff welcoming them back from a vineyard tour, or the warm scent of fresh bread wafting through the air during breakfast, making even the simplest moments feel indulgent.

boutique hotels in Wine Route Mendoza

Casa de Huéspedes Bodega Gimenez Riili

House
Ruta 94 Km 9 Camino al Manzano Histórico Los Sauces Tunuyan, 5561 Los Sauces, Argentina

Nestled in the serene embrace of the Andes, Casa de Huéspedes Bodega Gimenez Riili offers an exquisite escape where elegance meets nature. With its charming blend of modern comforts and rustic allure, this upscale guesthouse envelops you in tranquility, making it the perfect haven for romantic getaways and wellness retreats alike.

Romantic Retreat - Indulge in intimate moments as you wake up to breathtaking mountain views from your private terrace, where the sun’s first light casts a golden hue over the landscape, igniting a sense of wonder and romance that lingers throughout your stay.

Culinary Delights - Savor local flavors at our on-site restaurant, where each dish is expertly crafted using fresh ingredients. Relish in the aroma of a gourmet breakfast while gazing at the majestic Andes, or enjoy a cozy dinner complemented by fine wines produced right from our vineyard.

Nature's Playground - Explore the stunning surroundings with complimentary bicycles or embark on invigorating hikes, all the while being serenaded by the whispers of the wind through the trees and the vibrant colors of the local flora bursting into bloom.

Guest Experiences - As the sun dipped below the horizon, many found themselves captivated by the sounds of laughter and music floating from the outdoor fireplace area, where guests shared stories over cocktails, all while the delightful scent of grilled specialties wrapped around them, creating unforgettable memories.

boutique hotels in Wine Route Mendoza

Club Tapiz

Resort
Ruta 60 Kms 2.5, 5514 Chacras de Coria, Argentina

Nestled in the heart of Chacras de Coria, Club Tapiz invites you to escape into a haven of elegance and tranquility. This charming 1890s Renaissance villa, enveloped by lush vineyards and olive groves, provides an intimate backdrop for romantic retreats or serene solo getaways, where every moment is infused with the rich essence of Argentinian wine country.

Gastronomic Delights - Savor the flavors of the region in a candle-lit ambiance, where ruby red walls cradle your dining experience. Enjoy sumptuous breakfasts filled with fresh pastries and seasonal fruits, while each evening unfolds a culinary journey featuring homegrown organic produce that delights the palate.

Adventure Awaits - From horseback riding through scenic trails to exhilarating white-water rafting on Mendoza's pristine rivers, Club Tapiz offers a playground for adventure seekers. The majestic Cordillera de los Andes beckons with endless opportunities for trekking and canopy walks, ensuring every day is filled with excitement.

Wellness Retreat - Unwind in a sanctuary of serenity with rejuvenating massages at the wellness spa, or take a refreshing dip in the inviting pool. The soothing sounds of nature surround you as you relax after a day of exploration, creating a perfect balance of adventure and tranquility.

Guest Experiences - After an exquisite dinner, guests gather in the cozy living room, sharing stories over glasses of robust red wine and the crisp aroma of freshly pressed olive oil wafting from nearby tastings. The laughter of friends mingles with the soft crackle of the fireplace, crafting a warm tapestry of camaraderie that lingers in the air.

boutique hotels in Wine Route Mendoza

Villa Mansa

Hotel
Avenida Roque Saenz Peña 4900, Lujan De Cuyo, 5507 Vistalba, Argentina

Nestled in the serene embrace of Vistalba's vineyards, Villa Mansa exudes an enchanting charm that invites romance and relaxation. With its elegant spaces adorned in pastel hues and striking local art, this upscale retreat offers an intimate escape where every moment is infused with the spirit of Argentina's stunning countryside.

Romantic Retreat - Every room at Villa Mansa features a private balcony with breathtaking views, creating an idyllic backdrop for couples seeking solace and connection amidst nature’s splendor.

Culinary Delights - Savor a sumptuous buffet breakfast while basking in the soft morning light streaming through the restaurant’s expansive windows, or unwind later with gourmet dishes paired perfectly with exceptional local wines at the intimate Cava bar.

Wellness Oasis - Rejuvenate your senses with soothing massages or enjoy leisurely moments by the sparkling pool, enveloped in the tranquility of lush gardens that inspire ultimate relaxation.

Guest Experiences - As I sipped my morning coffee on the sun-drenched terrace, the aroma of freshly baked pastries mingled with the sweet scent of blooming flowers. The staff greeted me like an old friend, their warm smiles and genuine kindness made me feel truly at home, as if I were part of a family rather than just a guest.

boutique hotels in Wine Route Mendoza

Huentala Hotel

Hotel
Primitivo De La Reta 1007 Mza-Ciudad, 5500 Mendoza, Argentina

Nestled in the vibrant heart of Mendoza, Huentala Hotel invites discerning travelers to indulge in a sanctuary of elegance and comfort. With its serene swimming pool surrounded by lush greenery and an art gallery that whispers stories of local culture, this boutique hotel offers an intimate escape where luxury meets authenticity. It's not just a stay; it's an experience designed to awaken the senses and create lasting memories.

Artworks - Discover the intricate beauty of Mendoza through curated pieces in Huentala's art gallery, where each artwork breathes life into your surroundings and sparks curiosity as you wander through the halls.

Romantic Break - Soft hues and plush furnishings envelop you in a warm embrace, creating the perfect backdrop for romance—whether it’s a private dinner under the stars or a tranquil afternoon by the pool.

Wellbeing - Rejuvenate your spirit in the state-of-the-art fitness center or unwind in the sauna, as the soothing whispers of relaxation blend with the scent of lavender-infused oils wafting from the spa, promising a retreat for the senses.

Guest Experiences - As I settled into my room, the cool marble floor felt refreshing against my feet, while the soft hum of distant laughter mingled with the sweet aroma of breakfast pastries being prepared downstairs—an irresistible invitation to start the day.

boutique hotels in Wine Route Mendoza

Park Hyatt Mendoza Hotel, Casino & Spa

Hotel
Chile 1124, 5500 Mendoza, Argentina

Nestled in the heart of Mendoza, directly overlooking the vibrant Independencia Square, the Park Hyatt Mendoza Hotel, Casino & Spa effortlessly marries elegance with a sense of place. Its stunning architecture and luxurious surroundings invite you to drift into a world where every moment feels like a well-deserved escape, perfect for couples seeking romance or adventurers eager to explore local vineyards and culture.

Spa Retreat - Indulge your senses in an oasis of tranquility at the hotel’s spa, where soothing aromas blend with the soft sounds of water cascading in the hot tub. Experience personalized treatments that promise rejuvenation and serenity, allowing you to unwind completely amidst the bustling city life.

Culinary Delights - Savor culinary masterpieces at the Argentinean grill, where the sizzle of perfectly seared meats dances through the air, or unwind in Bistro M with its international flavors that transport you beyond borders. Each meal is not just food; it's a celebration of local ingredients and vibrant tastes, tantalizingly prepared by chefs who are passionate about their craft.

Central Location - With its prime location, you’re just steps away from the lively rhythms of Mendoza. Enjoy leisurely strolls through charming streets lined with boutiques and cafes, where the rich scents of freshly brewed coffee mingle with the laughter of locals enjoying their time outside.

Guest Experiences - One guest remarked on the sheer delight of waking up to the gentle hum of the city below, punctuated by the inviting aroma of fresh pastries wafting through the air during breakfast. Meanwhile, the concierge team, like Natasha and Luna, are known for creating memorable wine-tasting tours that feel less like errands and more like spontaneous adventures, making each interaction feel warm and personal.

Best Boutique Hotels with Spa that guests love in Wine Route Mendoza

boutique hotels in Wine Route Mendoza
Primitivo De La Reta 1007 Mza-Ciudad, 5500 Mendoza, Argentina
8.7
1618 reviews
From $170

Guest Review: There are three hotels, we're transfered to Sheraton which is beside Huentala.

boutique hotels in Wine Route Mendoza
Chile 1124, 5500 Mendoza, Argentina
8.9
1144 reviews
From $238

Guest Review: Second time in this hotel: big room, common areas and location. Breakfast is amazing and the staff is happy to help in everything you need.

boutique hotels in Wine Route Mendoza
Avenida Roque Saenz Peña 4900, Lujan De Cuyo, 5507 Vistalba, Argentina
9.0
446 reviews
From $245

Guest Review: Everything was great! Highly recommend it. Very quiet, staff super friendly and helpful. This is my third time staying and I enjoyed it so much.

Wine Route Mendoza Boutique Hotels on the Map

Frequently Asked Questions

For a luxurious spa experience in Wine Route Mendoza, consider staying at Park Hyatt Mendoza Hotel, Casino & Spa and Huentala Hotel. Both offer exceptional spa services along with stunning accommodations, making them ideal for travelers looking to unwind after a day of wine tasting.

Yes, for a romantic getaway in Wine Route Mendoza, you can choose Casa de Uco Vineyards and Wine Resort, known for its breathtaking vineyard views and elegant design, or Villa Mansa, which offers a serene atmosphere perfect for couples seeking intimacy among the beautiful landscapes.

Food enthusiasts will love Club Tapiz, which features a gourmet restaurant highlighting local flavors, and Casa de Huéspedes Bodega Gimenez Riili, where guests can enjoy wine tastings paired with delicious regional cuisine. Both options promise a delightful culinary experience!

For breathtaking vineyard views, consider Casa de Uco Vineyards and Wine Resort, perched among rolling hills, or Villa Mansa, offering expansive vistas of the vineyards and mountains. Both hotels provide an idyllic setting for nature lovers and wine aficionados alike.

If you're looking for great value, Huentala Hotel offers comfortable accommodations at competitive rates, while Club Tapiz combines affordability with high-quality dining experiences. Both options ensure a memorable stay without breaking the bank.

Absolutely! Park Hyatt Mendoza Hotel, Casino & Spa provides various amenities suitable for families, including spacious rooms and multiple dining options. Additionally, Huentala Hotel is known for its welcoming atmosphere and kid-friendly facilities, ensuring a comfortable stay for the whole family.