The 6 Best Boutique Hotels with Spa in San Isidro (2025)

Nestled in the lush suburbs of Buenos Aires, San Isidro enchants with its blend of historic charm and modern elegance. The picturesque streets are lined with stunning colonial architecture, vibrant gardens, and the striking silhouette of the San Isidro Cathedral, making it a delightful spot for leisurely exploration. As you wander through this captivating enclave, you’ll discover a flourishing culinary scene that celebrates both traditional Argentine flavors and contemporary innovations. In this inviting atmosphere, boutique hotels offer an unparalleled experience, characterized by their unique design and personalized service. Hotel del Casco stands out with its majestic 19th-century architecture and tranquil gardens, perfect for a romantic retreat. Meanwhile, Villa Isidro Hotel Boutique & Spa combines modern luxury with serene wellness options, ideal for those seeking relaxation. For a taste of urban sophistication, CasaSur Palermo Hotel offers stylish accommodations with easy access to local attractions. Each of these San Isidro boutique hotels with spa captures the essence of the city, inviting you to unwind in style. Start planning your unforgettable escape today!

List Of Best Boutique Hotels with Spa San Isidro

boutique hotels in San Isidro

Hotel del Casco

Hotel
Avenida del Libertador 16170, B1642CKV San Isidro, Argentina

Nestled in the enchanting enclave of San Isidro, Hotel del Casco invites you to step into a realm where luxurious neoclassical elegance meets the tranquil charm of its historic surroundings. As you ascend the grand marble staircase flanked by classic columns, you’ll feel the whispers of a storied past blend seamlessly with the modern comforts, creating an intimate escape that feels both exclusive and inviting.

Romantic Hideaway - With its lush gardens and elegant fountains, Hotel del Casco offers romantic corners perfect for stolen moments. Imagine sharing a sunset on your private terrace, surrounded by the soft murmur of cascading water and the fragrant blooms that fill the air.

Total Relaxation - Indulge in serenity at the health club, where the peaceful hum of the sauna and the gentle splash of the swimming pool transform each moment into pure bliss. A pampering massage awaits, offering a soothing escape that revitalizes both body and spirit.

Cultural Explorers - Situated in the heart of old San Isidro, the hotel serves as a perfect launchpad for cultural adventures. Stroll through cobblestone streets lined with historic architecture, quaint boutiques, and vibrant local markets, all while savoring the rich flavors of Argentine cuisine just a heartbeat away.

Guest Experiences - As one guest recalled, the hotel transforms breakfast into an experience—where the scent of freshly baked pastries mingles with the morning breeze, and friendly staff members ensure your coffee cup is never empty, creating a comforting ritual that feels like home.

boutique hotels in San Isidro

Villa Isidro Hotel Boutique & Spa

Hotel
Av. del Libertador 15935, 1642 San Isidro, Argentina

Nestled in the serene embrace of San Isidro, Villa Isidro Hotel Boutique & Spa transforms tranquility into an art form. With lush gardens and a shimmering pool that reflect the warm Argentine sun, this chic boutique retreat offers an intimate escape where luxury meets genuine hospitality—a perfect haven for romantic getaways and wellness seekers alike.

Total Relaxation - Indulge in rejuvenation at the spa, where soothing aromas of essential oils mingle with soft melodies, creating a sanctuary of serenity. Enjoy rejuvenating massages or relax in the dry sauna, allowing time to dissolve amidst tranquil surroundings.

Romantic Break - Each elegantly appointed room, adorned in soft beige tones, invites couples to unwind, with some featuring charming balconies overlooking the verdant garden, where the gentle rustle of leaves dances with the laughter of nearby birds—perfect for a morning coffee or an evening toast.

Intimate Escape - The hotel's intimate setting fosters connection, whether it’s sharing quiet moments by the poolside or exploring vibrant local markets just steps away. This boutique gem whispers romance through its decor and atmosphere, making every corner conducive to creating cherished memories.

Guest Experiences - One guest recounted a memorable evening spent lounging by the pool, where the scent of jasmine wafted through the air and the soft glow of string lights created an enchanting ambiance, while another delighted in the scrumptious pastries served during breakfast, their sweetness complemented by notes of freshly squeezed orange juice.

boutique hotels in San Isidro

CasaSur Palermo Hotel

Hotel
Costa Rica 6028, Palermo, 1452 Buenos Aires, Argentina

Nestled in the vibrant heart of Buenos Aires, CasaSur Palermo Hotel exudes an intimate luxury that whispers romance and relaxation. With its sleek modern design juxtaposed against the lively energy of the Palermo neighborhood, this oasis invites couples, travelers, and wellness enthusiasts to indulge in a uniquely Argentine experience, complete with attentive service and stylish touches.

Spa Retreat - Immerse yourself in tranquility as you unwind in the hotel’s spa and sauna facilities, where the gentle sound of soothing music mingles with the fragrant aroma of essential oils, creating a serene ambience for ultimate relaxation.

Culinary Delights - Savor the culinary creativity at the on-site restaurant, where each dish is a celebration of local flavors, inviting guests to indulge in a gastronomic journey that beautifully complements their stay.

Elegant Accommodations - Each room serves as a delightful sanctuary, fitted with plush bedding and tasteful décor that beckons you to sink into comfort; larger suites even feature cozy seating areas perfect for romantic evenings in.

Guest Experiences - As the sun sets over the bustling streets outside, the soft rustle of fresh linens fills the air, and the warm, welcoming smiles of the staff create an instant sense of belonging—an experience that feels like a home away from home.

boutique hotels in San Isidro

Fierro Hotel Buenos Aires

Hotel
Soler 5862, Palermo, 1425 Buenos Aires, Argentina

Nestled in the vibrant heart of Palermo Hollywood, Fierro Hotel Buenos Aires seamlessly blends chic sophistication with an intimate ambiance. Here, each modern room whispers luxury, inviting you to unwind amidst the gentle hum of this lively district, adorned with tantalizing aromas from nearby restaurants and a chorus of laughter spilling from cozy cafes.

Culinary Delights - Indulge your senses with a breakfast that feels like a feast; fresh pastries, aromatic coffee, and local delicacies await you, all lovingly served in a garden oasis where the scent of blooming flowers mingles with the morning air.

Spa Sanctuary - Retreat to the tranquil spa, where soft music carries you away as you relax by the soothing pool, enveloped in warmth and serenity. A sauna beckons those seeking rejuvenation, leaving you refreshed for another day of exploration.

Charming Location - Step outside and feel the pulse of Palermo Hollywood, where gastronomic treasures and eclectic shops are just a leisurely stroll away. The vibrant streets invite you to lose yourself in their charm, promising memorable adventures at every turn.

Guest Experiences - A delightful afternoon can unfold as you sip wine from a mini cava in your spacious room, the delicate clinking of glasses harmonizing with the hushed sounds of the city. Meanwhile, the attentive staff, eager to make your stay perfect, might surprise you with a flexible breakfast schedule, ensuring you never rush your first meal of the day.

boutique hotels in San Isidro

Home Hotel

Hotel
Honduras 5860, Palermo, C1414BNJ Buenos Aires, Argentina

Nestled in the vibrant heart of Buenos Aires, Home Hotel offers an exquisite escape where sophisticated design meets tranquil serenity. As you step into this urban oasis, you're enveloped in lush gardens and the soothing sounds of nature, creating a perfect backdrop for romance or relaxation amidst the city's pulse.

Chic Garden Retreat - Venture into our elegantly curated garden, where the air is fragrant with blooming flowers and fresh herbs, inviting you to unwind on comfortable loungers beneath shady trees—a true sanctuary within the bustling city.

Culinary Delights - Savor daily breakfasts that transform simple mornings into culinary celebrations, featuring artisanal pastries and homemade jams paired with freshly squeezed juices, while the acclaimed brunch menu showcases both local flavors and international dishes, making every meal a memorable affair.

Spa & Relaxation - Indulge in luxurious spa treatments designed to rejuvenate the body and spirit, where soothing aromas and soft music create an atmosphere of serenity—perfect for wellness enthusiasts seeking an escape from the everyday hustle.

Guest Experiences - Imagine sipping a refreshing cocktail by the pool as dusk settles, wrapped in the soft glow of twilight; as the gentle rustling of leaves serenades your ears, the attentive staff approaches, ready to fulfill even the smallest request with genuine warmth. It's those little touches, like finding your room adorned with fresh flowers, that make you feel truly at home.

boutique hotels in San Isidro

Boutique Suites Palermo

Hotel
Gorriti 5641, Palermo, 1414 Buenos Aires, Argentina

Nestled in the vibrant heart of Palermo Hollywood, Hotel BA Jardines Palermo is a sanctuary of chic elegance and tranquil comfort. With its lush gardens and inviting pool area, this boutique retreat envelops guests in a world where modern luxury meets the charming pulse of Buenos Aires, making it an idyllic escape for romance or rejuvenation.

Romantic Escape - Indulge in thoughtfully designed spaces where the soft glow of ambient lighting enhances your intimate moments, and the gentle sounds of nature create a serene backdrop to your stay.

Spa & Relaxation - Immerse yourself in a haven of tranquility within the on-site spa, where invigorating treatments and soothing aromas promise a restorative experience that revitalizes both body and spirit.

Outstanding Location - Step outside to discover the eclectic mix of local cafes, stylish boutiques, and vibrant galleries just moments from your door, allowing you to soak up the artistic essence of this lively neighborhood.

Guest Experiences - As you sip coffee in the charming breakfast nook, the delightful aroma of freshly baked pastries fills the air, while sunlight streams through the large windows, illuminating the friendly smiles of staff who are eager to share hidden gems around the city.

Best Boutique Hotels with Spa that guests love in San Isidro

boutique hotels in San Isidro
Gorriti 5641, Palermo, 1414 Buenos Aires, Argentina
7.8
1681 reviews
From $105

Guest Review: The breakfast was delicious and very nice for an included meal.

boutique hotels in San Isidro
Costa Rica 6028, Palermo, 1452 Buenos Aires, Argentina
8.3
566 reviews
From $660

Guest Review: Very polite and professional staff. Room clean and comfortable. Good location.

boutique hotels in San Isidro
Soler 5862, Palermo, 1425 Buenos Aires, Argentina
9.6
306 reviews
From $733

Guest Review: Friendly and welcoming. Adaptable for breakfast hours, 7:30 to 3 pm ! Small hotel with garden and roof pool.

San Isidro Boutique Hotels on the Map

Frequently Asked Questions

For an indulgent spa experience, consider staying at Villa Isidro Hotel Boutique & Spa or Home Hotel. Both hotels feature exceptional wellness services, including massages and rejuvenating treatments, perfect for travelers seeking relaxation within a stylish setting.

If you're looking for luxury, Hotel del Casco offers elegant accommodations with stunning architecture, while Fierro Hotel Buenos Aires is well-known for its modern design and upscale amenities that guarantee a lavish stay.

Yes! Villa Isidro Hotel Boutique & Spa provides a serene atmosphere perfect for couples, while Home Hotel features cozy rooms and charming decor, making both ideal choices for a romantic getaway.

Food enthusiasts will love CasaSur Palermo Hotel, known for its gourmet dining options, as well as Boutique Suites Palermo, which offers delicious local cuisine and a chic atmosphere that appeals to discerning palates.

For budget-conscious travelers, Home Hotel and Boutique Suites Palermo both offer stylish accommodations at competitive rates, ensuring a delightful stay without breaking the bank while still enjoying boutique amenities.