The 13 Best Boutique Hotels with Spa in Rest Of Dodecanese (2025)

Nestled on the serene hills of Karpathos Town, SOPHID Wellness Suites is an intimate retreat that blends modern luxury with the tranquility of nature. Here, the gentle sound of waves meets the aroma of fresh Mediterranean cuisine, creating an oasis where every moment is tailored for romance and relaxation.

Unparalleled Views - Gaze upon the mesmerizing Aegean Sea from your private terrace, where sunsets paint the sky in hues of orange and pink, while the surrounding mountains stand sentinel over this exquisite landscape.

Wellness Haven - Immerse yourself in a holistic experience, with a dedicated fitness center and rejuvenating spa services designed to refresh both body and soul, ensuring you leave feeling revitalized and balanced.

Culinary Delights - Savor each morning with a buffet breakfast featuring local delicacies and freshly made pastries, complemented by the warm aromas wafting through the open-air dining space, inviting you to linger longer over delightful conversations.

Guest Experiences - Upon arrival, guests are greeted with refreshing drinks and delectable desserts, setting the tone for their stay. One guest shared how they relished the luxurious ambiance as they enjoyed a leisurely breakfast, the sunlight kissing their skin while laughter echoed softly among the staff, making it feel like home.

Nestled on the enchanting island of Astypalaia, Chrysalis Boutique - Adults Only invites couples and discerning travelers to experience a haven of romance and tranquility. With breathtaking views of the shimmering Aegean Sea and the charming Chora old town, this boutique retreat blends modern luxury with intimate hospitality, offering a perfect escape for those seeking both adventure and serene relaxation.

Total Relaxation - Unwind in beautifully designed rooms that echo sophistication with airy balconies overlooking the mesmerizing sea and historic windmills. Each morning, enjoy breakfast on your terrace, where the fragrant aroma of freshly baked pastries mingles with the gentle sound of waves lapping against the shore.

Romantic Break - Whether you’re stargazing from your private balcony or savoring an evening drink at the chic bar, every moment at Chrysalis is tailored for lovebirds. The intimate ambiance encourages stolen glances and whispered secrets, creating lasting memories against a backdrop of stunning sunsets.

Outstanding Location - Just a short stroll from Pera Gialos Beach, the hotel seamlessly combines convenience with seclusion. Spend lazy afternoons cycling along coastal paths or exploring nearby historic sites, all while being enveloped by the island's breathtaking scenery.

Guest Experiences - Guests have relished delightful surprises, like having breakfast delivered right to their terrace, allowing them to sip rich coffee amidst panoramic views of the castle as the sun rises. The warmth and attentiveness of the staff often felt familial; they went above and beyond, arranging everything from transportation to personalized recommendations for hidden local gems.

Nestled in the heart of Astypalaia Town, Kallichoron Art Boutique Hotel is a serene oasis where artistic elegance meets eco-conscious luxury. Just a whisper away from the vibrant Chora square, this boutique hotel offers breathtaking views that blend the allure of history with the tranquil embrace of the Aegean Sea, creating an unforgettable backdrop for romance and relaxation.

Romantic Getaway - With stone-paved balconies opening to stunning vistas of the Venetian castle and sea, every moment invites intimacy and wonder—perfect for couples seeking a private escape.

Culinary Delights - Awaken your senses with the award-winning 'Grandma's breakfast,' a feast of Greek delicacies crafted with organic ingredients, where each bite tells a story of tradition and flavor, served against a backdrop of sweeping sea views.

Artistic Ambiance - Immerse yourself in a world of creativity as you stroll through spaces adorned with exquisite artworks from renowned artists, setting the stage for inspiration and contemplation throughout your stay.

Guest Experiences - Imagine waking up to the tantalizing aroma of fresh pastries wafting through your room, as you step onto your terrace to behold the sunrise casting golden hues over Chora; guests have delighted in friendly staff who remember their names and ensure every detail—like arranging a moped delivery for an afternoon adventure—is seamlessly catered to.

Nestled in the enchanting landscape of Astypalaia, Infinity Blue Suites & Spa offers an oasis of tranquility and refined luxury where every moment feels like a blissful escape. With its stunning vistas over the Aegean Sea and elegantly designed interiors that embrace both comfort and style, this haven invites couples, wellness enthusiasts, and cultural explorers to indulge in an unforgettable sojourn steeped in romance and relaxation.

Romantic Retreat - Every corner of Infinity Blue exudes intimacy, from candlelit dinners on private terraces to sun-kissed mornings by the sparkling pool, where laughter mingles with the sound of gentle waves lapping at the shore.

Spa Sanctuary - Immerse yourself in serene rejuvenation at the spa, where the scent of exotic oils fills the air as skilled therapists transport you to a world of blissful calm, ensuring each treatment leaves you feeling renewed and revitalized.

Outstanding Location - Just a stone's throw from the azure waters of Tzanakia Beach, guests can revel in leisurely strolls along the coastline, the salty breeze carrying whispers of local legends and the promise of adventure waiting just beyond the horizon.

Guest Experiences - The aroma of fresh pastries wafted through the hotel every morning, making breakfast not just a meal, but a delightful ritual. Guests often found themselves struck by the warmth of the staff—one guest recalled a heartfelt conversation over coffee, where the owner shared stories about the island’s hidden gems.

Nestled on the charming island of Symi, The Old Markets invites you into a world where elegance meets authenticity. With lush gardens and sun-drenched terraces overlooking the harbor, this boutique haven serves as an idyllic escape for those seeking romance or relaxation amidst the vibrant hues of Greek life.

Romantic Break - With its secluded ambiance and stunning views, The Old Markets creates an intimate setting perfect for couples looking to deepen their connection in a picturesque environment.

Total Relaxation - Guests indulge in tranquil moments surrounded by beautifully curated decor, where every detail—from the plush linens to the gentle sounds of nature—whispers comfort and serenity.

City Style - Located just a short stroll from local markets and scenic beaches, the hotel offers easy access to the vibrant culture of Symi while providing a chic retreat to unwind after a day of exploration.

Guest Experiences - Awakening to the sweet aroma of freshly brewed coffee wafting through the balcony doors, guests often find themselves enchanted by the breathtaking views of the harbor, enjoying breakfast served with a personal touch that makes each morning feel extraordinary.

Nestled in the serene embrace of Grikos Bay, Patmos Aktis, a Luxury Collection Resort & Spa, offers an enchanting retreat where luxury meets tranquil seclusion. With every room just steps from the soft sands of a private beach, this exquisite haven invites you to indulge in breathtaking views, sumptuous culinary experiences, and rejuvenating spa treatments—all within the backdrop of Greece's timeless beauty.

Beach Life - Savor the gentle lapping of waves as you relax on your private beach, complete with plush loungers and personalized service that ensures your every need is catered to, from refreshing towels to chilled water bottles delivered to your door each evening.

Spa Breaks - Rejuvenate your spirit in the opulent spa, where the scent of essential oils intertwines with the sound of soothing melodies, creating a sanctuary for the senses; whether indulging in a revitalizing massage or unwinding in the whirlpool, self-care has never felt so luxurious.

Romantic Getaway - Experience intimate dining at Cielo e Mare, where candlelight dances upon your table as you savor exquisite Mediterranean flavors, each dish crafted from the freshest local ingredients, while the ocean breeze whispers sweet nothings into the night.

Guest Experiences - One morning, the aroma of freshly brewed coffee wafted through the air, perfectly complementing the vibrant breakfast buffet, where guests marveled at the array of options while enjoying the stunning sea views that made each meal a feast for the senses.

Nestled on the sun-kissed shores of Masouri, Carian Hotel offers an intimate escape where luxury meets tranquility. With sweeping views of the Aegean Sea and a serene atmosphere, each moment here feels like a gentle embrace from paradise.

Breathtaking Views - Gaze out over the azure waters as the sun dips below the horizon, painting the sky with vivid oranges and pinks. Each room is a sanctuary, featuring expansive balconies that invite you to linger and savor the beauty of Telendos Island just off the coast.

Spa Retreat - Step into a realm of relaxation at our inviting spa, where the soothing aroma of essential oils envelops you. Indulge in rejuvenating treatments, unwind in the hot tub, or simply bask in the tranquility of the steam room—your personal oasis awaits.

Culinary Delights - Start your day with a delightful Greek buffet breakfast, rich with fresh local flavors and traditional dishes. The inviting aromas from the on-site restaurant weave through the air, making it impossible to resist the tantalizing snacks offered throughout the day.

Guest Experiences - Guests have described their mornings as magical, waking to the sound of gentle waves lapping against the shore and enjoying coffee on their balcony while soaking in the breathtaking views. The friendly staff is known for their warm smiles and thoughtful gestures, ensuring every detail adds to the charm of your stay.

Nestled on the enchanting island of Astypalaia, Studios Kilindra invites you to experience a serene blend of luxury and intimacy. With breathtaking views over the shimmering Aegean Sea and the historic castle perched above, each moment spent here feels like stepping into a personal paradise, where every detail whispers elegance and warmth.

Stunning Sea Views - Each room at Studios Kilindra offers uninterrupted vistas that transform with the light, painting your mornings with golden rays and evenings with hues of lavender at sunset. Step onto your private balcony, and let the soothing sounds of the waves wash over you as you sip your morning coffee.

Tranquil Pool Oasis - The picture-perfect pool invites you to unwind under the Grecian sun, surrounded by lush landscapes and comfortable loungers. As you dip into its refreshing waters, the gentle breeze carries hints of local flora, creating an atmosphere of pure relaxation.

Culinary Delights in Paradise - Indulge in a delightful breakfast served beside the pool, where fresh pastries and ripe fruit tantalize your senses. The aroma of rich coffee mingles with the salty sea air, making each bite a celebration of local flavors amidst an idyllic setting.

Guest Experiences - One evening, guests lingered at the tranquil pool area, enchanted by the extraordinary view—a panorama so captivating that time seemed to stand still. The sounds of laughter mixed with the gentle splash of water created a perfect backdrop, while the warm glow from nearby lanterns cast a magical ambiance.

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Nestled in the heart of Karpathos Town, Nereides Hotel is a lavish retreat that seamlessly melds modern elegance with timeless Greek charm. Just a gentle stroll from the azure waters of Afoti Beach, this boutique haven invites you to indulge in serene luxury, where every moment feels like an exquisite romance painted against a sun-drenched canvas.

Romantic Retreat - With its intimate ambiance and chic decor, Nereides Hotel is the perfect sanctuary for couples seeking a romantic escape. Picture candlelit dinners by the pool, where laughter mingles with the soft rustle of palm leaves, creating an atmosphere of pure enchantment.

Spa & Relaxation - Unwind at the tranquil outdoor swimming pool, surrounded by lush gardens that whisper serenity. The refreshing scent of blooming flowers fills the air as you sip on a cool drink, allowing the stresses of everyday life to simply melt away.

Outstanding Location - Positioned within walking distance of both the vibrant Pigadia Port and the laid-back allure of local markets, Nereides Hotel offers guests the rare opportunity to immerse themselves in the rich cultural tapestry of Karpathos. Stroll through charming streets buzzing with life, or retreat to hidden corners for a quiet afternoon of people-watching.

Guest Experiences - As dawn breaks, the aroma of freshly baked bread wafts from the breakfast area, inviting guests to savor an array of delightful options that feel homemade. One guest recalled how the attentive staff surprised them with a complimentary late check-out, allowing for a blissful final morning swim before leaving this slice of paradise.

Nestled on the enchanting island of Astypalea, Pylaia Boutique Hotel & Spa beckons with its luxurious charm and breathtaking views. Perched gracefully on a hillside, each moment at this elegant retreat feels like a serene escape, where the azure sea dances on the horizon and the gentle breeze carries whispers of romance.

Total Relaxation - Indulge in the tranquil ambiance of the Pylaia Spa, where the soothing scent of essential oils envelops you as expert hands work their magic. With complimentary access to the steam bath and whirlpool, every corner invites relaxation and rejuvenation.

Romantic Break - With stunning vistas overlooking the castle of Astypalea, intimate dinners at the hotel's restaurant are transformed into magical evenings. Picture candlelit tables where the soft murmur of the waves harmonizes with laughter and clinking glasses under a starlit sky.

Outstanding Location - Just a short stroll from the bustling heart of Chora, you're close enough to feel the pulse of local life yet distanced enough to relish peace. Delight in the vibrant colors of the nearby markets or wander down to Livadi beach for sun-soaked afternoons.

Guest Experiences - Guests have marveled at the delightful breakfast spread, savoring the aroma of fresh coffee mingling with the sweet scent of homemade pastries. One visitor recalled how the owner's personalized touch—organizing an unforgettable boat cruise to hidden gems around the island—made their stay truly special.

Nestled along the golden shores of Kefalos, Ikos Aria is a luxurious haven where modern elegance meets the serene embrace of nature. The gentle sound of waves lapping at the beach harmonizes with laughter from the vibrant kids' club, creating an inviting atmosphere perfect for families and couples alike. As the sun sets, the air fills with the aroma of Mediterranean cuisine wafting from the on-site restaurant, promising delightful culinary adventures in every bite.

Total Relaxation - Unwind in style at the stunning outdoor swimming pool, where plush loungers beckon you to bask in the sun while sipping on a refreshing cocktail. The serene surroundings and attentive service invite you to indulge in pure tranquility, making every moment a cherished escape.

Spa Breaks - Immerse yourself in the hotel’s spa sanctuary, where soothing aromas and the soft hum of relaxation envelop you. Experience rejuvenating treatments that restore your body and spirit, ensuring you leave feeling completely renewed and invigorated.

Beach Life - Step into paradise as you stroll just a short distance to Paralia Kefalos Beach, where the azure waters greet you with gentle waves and soft sands. Each day presents a new opportunity for adventure, whether it’s kayaking across the shimmering sea or simply lounging under the sun's warm embrace.

Guest Experiences - One guest recalled hearing delighted giggles from the Kids Club, where the team, particularly the charismatic Lilia, transformed daily activities into magical moments. Meanwhile, the evening theater performances dazzled families, leaving them enchanted by the unexpected quality and creativity of the shows.

Nestled gracefully on the sun-kissed hills of Kefalos, the White Rock of Kos Hotel - Adults Only offers an exquisite retreat where romance flourishes and tranquility reigns. With panoramic views of the Aegean Sea and an ambiance steeped in elegance, this five-star sanctuary invites couples and discerning travelers to indulge in luxury while basking in the serenity of their surroundings.

Romantic Break - Framed by stunning vistas, intimate poolside cabanas beckon you to unwind with a glass of local wine as the sun sets, painting the sky in hues of pink and gold—a perfect backdrop for cherished moments.

Spa Breaks - Immerse yourself in rejuvenation at our serene spa, where soothing aromas weave through the air. Experience indulgent treatments that not only restore your body but also elevate your spirit amidst the sound of gentle waves lapping at the shore below.

Private Hot Tub - Select suites feature luxurious private hot tubs, offering an enchanting way to soak under the stars, surrounded by the soft glow of the moonlight—a dreamy escape where every moment feels like a blissful embrace.

Guest Experiences - As dawn breaks, guests awaken to the scent of fresh pastries wafting from the kitchen, mingling with the salty sea breeze. One couple recalls the delight of a leisurely breakfast on their terrace, where each bite was accompanied by breathtaking views of the bay, inspiring them to stay just a little longer.

Nestled along the sun-kissed shores of Kardamaina, Mitsis Selection Blue Domes encapsulates the essence of a luxurious Greek retreat. Here, the gentle lullaby of the waves harmonizes with the vibrant colors of Mediterranean sunsets, creating an atmosphere that beckons romance and relaxation in equal measure.

Total Relaxation - Immerse yourself in the serene ambience of the on-site spa, where the delicate scent of essential oils wafts through the air as you indulge in rejuvenating treatments designed to melt away your stress.

Beach Life - Step out onto soft sands that glisten under the Aegean sun, where days are filled with the joyful sounds of laughter from children splashing in the turquoise waters and evenings invite you to stroll along the shore as the sky transforms into a canvas of stars.

Outstanding Location - Situated just a stone's throw from the charming village of Kardamaina, guests can effortlessly blend relaxation with exploration—basking in local markets brimming with artisanal crafts and savoring the flavors of traditional Greek tavernas nearby.

Guest Experiences - Guests have commented on the impeccable attention from the staff, who greet you with genuine smiles—it's not uncommon to overhear the soft clinks of glasses as a bartender happily prepares your favorite cocktail while you lounge by the pool, soaking in the tranquil atmosphere.