The 14 Best Boutique Hotels with Spa in Midwest (2025)

Nestled in the heart of Wausau, Wisconsin, Stewart Inn offers an enchanting retreat where modern elegance meets timeless charm. As you step inside, the inviting aroma of freshly brewed coffee mingles with the soft rustle of linens, creating a sanctuary that beckons couples, wellness seekers, and cultural explorers alike to unwind and savor life’s simple pleasures.

Culinary Delights - Savor an exquisite breakfast experience that tantalizes the palate, featuring carefully crafted dishes that range from hearty English fare to vibrant vegan options. Each morning unfolds like a celebration, with guests sharing laughter over three-course meals that inspire delightful conversation.

Intimate Elegance - Every room at Stewart Inn is a haven of comfort, adorned with plush bedding and thoughtful amenities. The gentle hum of a Blu-ray player sets the backdrop for cozy evenings, while select rooms offer scenic balconies to enjoy the tranquil garden views, wrapping you in an atmosphere of refined relaxation.

Adventure Awaits - Embrace the spirit of exploration with activities that surround this charming inn, from invigorating hikes along picturesque trails to exhilarating skiing adventures. Each season unveils new opportunities for thrill-seekers and nature lovers alike, making every visit a unique journey into the heart of Wausau.

Guest Experiences - As dawn breaks, the sumptuous scent of Randy’s specially prepared breakfast wafts through the air, awakening senses with promises of culinary delight. Guests find themselves captivated by the warmth of the inn's aesthetics—a stunning blend of historic character and immaculate cleanliness—that feels less like a hotel and more like the welcoming embrace of a dear friend.

Step into a world where history meets modern luxury at the Bottleworks Hotel, nestled in the heart of Indianapolis. This beautifully renovated landmark whispers tales of its Art Deco past while inviting you to experience contemporary elegance and upscale comfort, making it the perfect romantic getaway or luxurious retreat for the discerning traveler.

Romantic Break - With intimate ambiance and chic decor that echoes its historic roots, the Bottleworks Hotel sets the stage for unforgettable moments. Stroll hand-in-hand along Massachusetts Avenue, then return to unwind in your spacious sanctuary, where plush bedding and sumptuous showers await.

Boutique - Each corner of the hotel is adorned with curated artwork and playful design elements, offering a sensory feast that invites exploration. Whether it's the bubbling water fountains or the intricate details of the original architecture, this boutique gem transports you to a realm of artistic inspiration.

Spa breaks - Indulge in self-care at the on-site spa, where serenity envelops you in soothing scents and tranquil sounds. After a rejuvenating treatment, retreat to the serene terrace and bask in the gentle Indiana breeze as you sip on a craft cocktail.

Guest Experiences - Upon entering the hotel, the air carries a delightful mix of fresh coffee and subtle floral notes from the nearby fountains. One guest marveled at their spacious room, declaring the bed 'super comfy' while reminiscing about the warmth of the staff—especially Renee, whose genuine concern helped reunite them with their forgotten bag, turning a routine check-in into an incredibly personal experience.

Nestled in the vibrant heart of Indianapolis’ north side, Ironworks Hotel Indy is more than a boutique stay; it’s a romantic retreat where modern elegance meets rustic charm. With its tantalizing aromas wafting from upscale dining and an inviting rooftop lounge that beckons couples to unwind beneath starry skies, this hotel promises a luxurious yet intimate escape for discerning travelers.

Chic Accommodations - Every room at Ironworks balances sophisticated rustic décor with contemporary comforts, featuring plush bedding and walk-in showers framed by frosted glass—an indulgent treat for couples seeking seclusion and style.

Culinary Discoveries - Savor craft cocktails and exquisite dishes at Provisions, where the bartenders greet you with genuine warmth as you sip drinks infused with local flavors, setting the stage for memorable evenings filled with laughter and connection.

Wellness & Relaxation - The sleek fitness center invites guests to maintain their routines, while the serene atmosphere throughout the hotel encourages moments of quiet reflection—perfect for wellness enthusiasts looking to recharge amidst urban excitement.

Guest Experiences - Guests often speak fondly of the delightful scent that greets them upon entering, reminiscent of rich coffee and artisanal pastries, creating a warm ambiance that feels like home. The enchanting raindrop shower has become a highlight, providing a soothing experience that guests can't stop raving about, making each moment spent there feel refreshingly special.

Nestled along the iconic Magnificent Mile, The Peninsula Chicago envelops guests in an exquisite blend of modern elegance and timeless charm. From the moment you step inside, the air is infused with a soothing ambiance, inviting both relaxation and indulgence amidst the city's vibrant energy.

5* Luxury - Step into spacious luxury guest rooms that exude sophistication, featuring sumptuous fabrics and breathtaking city views, where every detail—from the plush bedding to the ambient lighting—invites you to unwind in style.

Spa breaks - Experience total tranquility at the full-service Asian-inspired spa, where the scent of essential oils mingles with soft music, creating an oasis for wellness enthusiasts seeking rejuvenation and peace amid the urban bustle.

City Style - Immerse yourself in Chicago's unique allure as you explore local markets and cultural gems just moments away, with the historic Water Tower Place beckoning across the street and the stunning Navy Pier a leisurely stroll away.

Guest Experiences - Guests rave about the delightful surprise of a warm welcome from staff who anticipated their needs, crafting a stay filled with thoughtful amenities, like comfort kits provided after luggage mishaps, alongside the gentle hum of city life filtering through expansive windows.

Nestled in the heart of Kansas City, The Raphael Hotel, Autograph Collection offers an exquisite blend of historic charm and modern elegance. With its warmly lit interiors, eclectic artworks, and the gentle sound of live music wafting through the lobby, every corner invites you to pause and savor the moment, whether you're indulging in a cozy afternoon with freshly baked cookies or retreating to your luxurious room for a night of tranquility.

Romantic Getaway - Perfectly tailored for couples, this hotel is a sanctuary where intimacy reigns supreme, from candlelit dinners in the in-house restaurant to strolling hand-in-hand through the nearby Plaza's vibrant art scene.

Boutique Charm - Every detail at The Raphael whispers sophistication—think plush furnishings, elegant décor, and a unique character that transcends the ordinary, allowing guests to immerse themselves in an experience that's both cozy and chic.

Culinary Delights - Start your morning with enticing brunch options served until 2 PM, where each dish is crafted to perfection, making breakfast in bed a truly delightful experience, all while the enchanting aromas from the kitchen mingle softly with the music playing in the background.

Guest Experiences - Guests rave about the warmth that envelops them upon entering; the delightful scent of freshly baked cookies beckons from the lobby each afternoon, while the soothing sound of chilled towels being handed out at the gym adds a touch of luxury to their wellness routine.

Nestled in the vibrant heart of Milwaukee, The Pfister Hotel transcends the ordinary with its exquisite blend of historic charm and modern luxury. As you step into this opulent haven, the scent of fresh blooms mingles with the subtle echoes of soft jazz, inviting you to unwind in an atmosphere steeped in elegance and romance.

Total Relaxation - Indulge in a rejuvenating escape at the full-service spa, where the gentle sound of flowing water accompanies your journey to tranquility. Each treatment is tailored for blissful relaxation, allowing you to fully immerse yourself in self-care amidst opulent surroundings.

Outstanding Location - Just a leisurely stroll from the iconic Milwaukee Art Museum, The Pfister places you at the center of cultural exploration. With the city's vibrant art scene and lively markets within easy reach, every moment spent here is infused with local character and charm.

Romantic Break - Elevate your getaway with breathtaking views from Blu, the martini bar perched high on the 23rd floor. Sip on expertly crafted cocktails as the sun sets over the city skyline, enveloping you in a warm glow that perfectly complements a dreamy evening.

Guest Experiences - One guest reminisced about the delightful breakfast in the cafe, describing the aroma of freshly brewed coffee and warm pastries wafting through the air, paired with attentive service that made them feel like royalty. Another was captivated by the intricate details adorning the lobby, feeling as though they were stepping into a living museum where each corner revealed a story.

Nestled in the heart of Chicago, The Langham exudes a sophisticated elegance that invites guests to indulge in a world where luxury meets unparalleled service. This architectural marvel, designed by Mies van der Rohe, offers a serene retreat just moments from the vibrant energy of Michigan Avenue, ensuring every moment spent within its walls feels like a cherished escape.

Romantic Hideaway - With warm tones and dark wood accents, the rooms create an intimate ambience, enhanced by floor-to-ceiling windows framing stunning views of the city skyline and shimmering Lake Michigan, making each moment feel like a scene from a romantic film.

Spa and Wellness Retreat - Chuan Spa beckons with its soothing aromas and tranquil atmosphere, offering rejuvenating treatments inspired by Traditional Chinese Medicine that promise to melt away stress and transport you to a place of serenity, especially after a long day of city exploration.

Culinary Delights - At Travelle, seasonal American cuisine is presented with flair, infusing modern flavors into traditional favorites, while the elegance of afternoon tea at Pavilion invites you to savor exquisite Langham teas paired with delightful sweet and savory treats, amidst the gentle sound of clinking cups.

Guest Experiences - Upon arrival, the sweet scent of freshly brewed tea wafts through the air as guests recount their first impressions—a delightful champagne tea greeted them, followed by the plush comfort of impeccably clean rooms, where soft linens invite you to sink into relaxation, punctuated only by the faint sounds of laughter from the bar below.

Nestled in the heart of Chicago, just a whisper away from the iconic Water Tower Park and vibrant Michigan Avenue, the reimagined Park Hyatt Chicago transcends the ordinary, offering an elegant retreat for discerning travelers. Here, the energy of the city converges with moments of tranquility, creating a luxurious home away from home where every detail is curated for comfort and sophistication.

Outstanding Location - With its prime address, guests are perfectly positioned to explore the dynamic streets of Chicago, from designer boutiques to stunning cultural enclaves, all within walking distance. The gentle hum of the city outside serves as a vibrant backdrop to your stay.

Total Relaxation - Embrace serenity in the thoughtfully designed spaces that feature calming tones and plush furnishings, allowing you to unwind after a day of exploration. Each suite invites you to sink into the lavish bedding, where the soft whispers of Lake Michigan can be heard, lulling you into a peaceful slumber.

Spa Breaks - Indulge in a rejuvenating escape at the hotel's spa-like amenities, including a tranquil indoor pool that beckons with sparkling waters. Upgraded wellness facilities ensure your body and mind are as pampered as your spirit, providing the ultimate sanctuary amidst the urban bustle.

Guest Experiences - As the sun dipped below the skyline, one guest recalled savoring a casual breakfast while breathing in the rich aroma of freshly brewed coffee wafting from the restaurant. They marveled at how the staff's warm smiles made them feel like cherished family, even when their table was momentarily hard to secure.

Nestled in the heart of downtown Louisville, the 21c Museum Hotel seamlessly blends contemporary art with luxurious accommodations, crafting an enchanting retreat for couples and cultural explorers alike. As you step into this vibrant space, the air is infused with a sense of creativity, inviting you to indulge in both relaxation and artistic inspiration.

Artworks & Culture - Immerse yourself in a dynamic fusion of art and hospitality, where each corner reveals thought-provoking installations that spark conversation and ignite your imagination.

Outstanding Location - Ideally situated just steps away from the city's iconic attractions, venture out to discover the rich history of Louisville or savor the local culinary scene without ever needing to stray far from your elegant oasis.

Spa & Wellness - Unwind in the tranquil spa, where soothing scents of essential oils mingle with soft music, providing an escape from the hustle and bustle of city life while rejuvenating your body and spirit.

Guest Experiences - Guests often recount the moment they first entered their spacious room, greeted by plush bedding and the subtle scent of fresh lavender; it's a cozy haven that makes you feel instantly at home, complemented by the friendly staff who remember your name as if you were family.

Nestled in the heart of Sioux City, The Warrior Hotel, Autograph Collection invites you to indulge in a serene haven of elegance and romance. With its historic charm beautifully interwoven with modern luxury, every corner whispers stories of the past while offering an oasis for relaxation and rejuvenation.

Total Relaxation - Unwind in the tranquility of our spa and wellness center, where the soothing sounds of water from the indoor pool harmonize with the gentle hum of the hot tub, creating a perfect backdrop for your retreat.

Romantic Break - Imagine sipping wine on a private terrace as the sun sets over Sioux City's skyline, the warm glow wrapping around you like a cozy blanket—a truly enchanting escape that sparks connection and intimacy.

Outstanding Location - Step outside and find yourself within walking distance of vibrant local culture, including the Sioux City Art Center and the bustling Tyson Events Center, allowing you to immerse yourself in the city's artistic heartbeat.

Guest Experiences - As you enter your room, the plush textures and elegant decor invite you to kick off your shoes and sink into the inviting chair; the quietude is punctuated only by the distant whir of life outside, ensuring a peaceful night's rest.

Nestled amidst Chicago’s architectural marvels, Trump International Hotel & Tower Chicago offers a symphony of luxury, elegance, and panoramic beauty. With floor-to-ceiling windows framing breathtaking views of Lake Michigan and the bustling city skyline, each moment spent in this towering sanctuary is wrapped in an intimate embrace of sophistication and tranquility.

Outstanding Location - Perfectly situated just steps from the vibrant energy of Michigan Avenue’s Magnificent Mile, this hotel invites guests to explore upscale shopping, gourmet dining, and lively cultural attractions right at their doorstep.

Romantic Retreat - With its plush furnishings and serene atmosphere, the hotel becomes a haven for couples, where candlelit dinners on the seasonal terrace provide the backdrop for unforgettable moments against the stunning skyline.

Spa & Relaxation - Indulge in rejuvenating spa services that blend tranquility with indulgence, offering treatments that awaken the senses while enveloping you in the soothing ambiance of this luxurious oasis.

Guest Experiences - Guests have remarked on the delightful attentiveness of the staff, who seem to anticipate needs before they arise—whether it’s a warm greeting or a perfectly poured cocktail—with the inviting aroma of fresh sushi wafting through the air at Rebar, setting the stage for a truly memorable evening.

Nestled amid the tranquil landscapes of Camdenton, The Lodge at Old Kinderhook embodies an oasis of elegance and comfort. With its modern design interwoven with rustic charm, this luxurious retreat invites couples and seekers of serenity to indulge in romantic evenings by the fireplace or leisurely afternoons lounging poolside, surrounded by lush gardens and whispering pines.

Romantic Getaway - Feel the allure of intimacy as you unwind in elegantly appointed rooms, each a sanctuary that beckons with plush linens, soft lighting, and breathtaking views of the serene landscape. The ambiance is perfectly set for those cherished moments together, whether sipping wine on your private terrace or sharing laughter over candlelit dinners.

Wellbeing Retreat - Discover revitalization at the state-of-the-art spa, where scents of essential oils fill the air, and soothing sounds create a symphony of relaxation. Guests can immerse themselves in rejuvenating treatments or simply bask in the warmth of the hot tub, enveloped by the calming sights of nature's tapestry outside.

Outdoor Adventures - Step outside and embrace the thrill of adventure with tennis courts and scenic hiking trails just moments away. Each trek unveils stunning vistas, while the brisk air invigorates your spirit; the experience captures the essence of a true escape into nature’s embrace.

Guest Experiences - One guest delighted in the sweet fragrance of freshly brewed coffee wafting through the halls each morning, setting the perfect tone for another day of exploration. As they settled onto their balcony, the peaceful sounds of nature created a serene backdrop, punctuated only by the occasional laughter from families enjoying the pools nearby.

Nestled at the crossroads of Michigan Avenue and the mesmerizing Chicago River, LondonHouse Chicago offers an enchanting blend of historic elegance and modern luxury. With its iconic tri-level rooftop bar, this gem invites couples and travelers alike to unwind amidst breathtaking skyline views and refined ambiance, making every moment feel like a cherished escape.

Romantic Retreat - Indulge in a chic sanctuary where plush accommodations meet stunning river vistas, creating the perfect backdrop for intimate getaways and memorable honeymoon moments.

Culinary Delights - Savor reimagined regional cuisine at LH, where each dish is crafted to perfection and enjoyed under the grand 23rd story domed cupola, with the sounds of the city harmonizing with every delightful bite.

Outstanding Location - Situated mere steps from Millennium Park and famed cultural hotspots, guests can effortlessly explore the vibrant art scene and rich history that Chicago has to offer, all while returning to their serene haven.

Guest Experiences - Awaken to the soft patter of rainfall against your window, as you sip on fresh coffee and take in the captivating river view; guests rave about those quiet mornings that transform into vibrant afternoons spent lounging on the rooftop terrace, where laughter mingles with the cool breeze.

Nestled on the shimmering shores of Lake Ozark, Camden on the Lake Resort invites you to indulge in an oasis of elegance and tranquility. The gentle lapping of water against the marina blends seamlessly with the laughter of friends gathered around the swim-up pool bar, crafting a perfect backdrop for romantic getaways or rejuvenating escapes. Each moment here is drenched in luxury, creating an inviting atmosphere that feels both exclusive and intimately welcoming.

Spa Breaks - Rejuvenate your senses at the full-service spa, where soothing aromas and tranquil music envelop you as skilled therapists guide you into blissful relaxation. Whether it’s a couples’ massage or a skin-revitalizing treatment, every experience is tailored to refresh both body and mind.

Lakeside Escape - With views that stretch endlessly over the lake, each spacious suite allows you to bask in the natural beauty of your surroundings from your private balcony. Picture yourself sipping morning coffee while soft rays of sunlight dance on the water’s surface, setting the tone for another glorious day.

Active Holiday - For those seeking adventure, water sports abound just steps away from your door. From windsurfing across the sparkling lake to savoring a thrilling ride on water skis, excitement is never far from reach, promising unforgettable memories filled with laughter and exhilaration.

Guest Experiences - As you stroll through the resort, the sound of live music wafts through the air during seasonal concerts, drawing you toward the vibrant energy of the outdoor space. Guests often remark on the comfort of their rooms, where plush beds beckon after a long day of exploration, making it easy to drift off to sleep with the gentle hum of the lake as your lullaby.