The 5 Best Boutique Hotels with Spa in Florida Keys (2025)

Nestled among lush tropical foliage, The Gardens Hotel is a serene adult-only retreat in the heart of Key West, where each moment feels like an intimate escape. With fragrant blooms filling the air and the gentle sound of rustling leaves, this upscale haven invites couples and romantic travelers to unwind in its elegant ambiance, just steps away from the vibrant pulse of Duval Street.

Romantic Retreat - With private balconies overlooking verdant gardens, every room at The Gardens Hotel offers a tranquil space to bask in the romance of island life. The soft whisper of palm fronds swaying creates a soothing backdrop for candlelit evenings and leisurely mornings.

Charming Oasis - Two inviting outdoor pools beckon you to lounge under the sun or find solace in shaded nooks, while the property’s hidden hammocks offer perfect spots for afternoon daydreams. Guests often delight in discovering quiet corners, making it feel like a personal sanctuary amidst the lively surroundings.

Live Entertainment - Every Sunday evening, immerse yourself in the soulful sounds of live jazz as it serenades the garden, creating a magical atmosphere that enhances the romantic setting. The enchanting melodies blend seamlessly with the evening breeze, painting memories that linger long after your stay.

Guest Experiences - As you sip coffee by the poolside, the aroma of freshly prepared breakfast wafts through the air, teasing your senses with promises of delightful flavors. A chance encounter with the gracious owner adds a personal touch, leaving guests feeling not just welcomed but truly at home in this beautiful, immaculately kept oasis.

Nestled just a block away from the shimmering Atlantic Ocean and the vibrant pulse of Duval Street, Santa Maria Suites Resort is an intimate oasis that blends modern luxury with the charming quirks of Key West. Here, spacious all-suite accommodations invite you to unwind in style, surrounded by lush gardens and the gentle sound of water lapping at nearby shores, creating an atmosphere ripe for romance and relaxation.

Romantic Retreat - Indulge in the ultimate romantic escape, where each suite offers stunning decor and a full kitchen, perfect for intimate dinners or lazy breakfasts in bed, complemented by the scent of fresh muffins wafting through your door each morning.

Total Relaxation - Two heated outdoor pools beckon for leisurely dips amidst tropical gardens, while complimentary poolside smoothies refresh your spirit under the warm Florida sun—a dreamy backdrop for unwinding after exploration.

Outstanding Location - Just moments from historic sites and local markets, you can easily stroll to iconic attractions like the Ernest Hemingway House, returning to the sanctuary of your suite equipped with everything you need—truly a hub for cultural explorers and adventure seekers alike.

Guest Experiences - Guests have delighted in the unexpected treats awaiting them daily: imagine opening your suite to the allure of freshly baked muffins alongside Dove ice cream mini bars, while the friendly staff members, particularly Matilda, go above and beyond, offering personalized tips on dining and sights with genuine warmth.

Nestled along the pristine shores of Key Largo, Bungalows Key Largo - All Inclusive beckons couples and romantic travelers into a world where luxury meets tranquility. Each luxurious bungalow serves as a private sanctuary, complete with soothing ocean breezes and breathtaking views, ensuring that every moment is tailored for relaxation and intimate connection.

Total Relaxation - Indulge in the serene atmosphere as you bask by the shimmering pools or unwind in your own private hot tub under a starlit sky, where the only sound is the gentle lapping of waves on the shore.

Spa Breaks - Rejuvenate your senses at the full-service spa, where expert therapists blend natural ingredients into treatments designed to melt away stress, leaving you enveloped in tranquility and bliss.

Boutique Beach Life - Discover an exclusive stretch of golden sand where soft towels await, inviting you to sink into plush lounge chairs while sipping on expertly crafted cocktails, all against a backdrop of sapphire waters and swaying palms.

Guest Experiences - As you stroll through the lush grounds, the fragrant aromas of gourmet dishes waft invitingly from the nearby restaurants, mingling with the sounds of laughter from guests savoring sunset sails, capturing the heart of what makes this resort feel like a home away from home.

Nestled along 14.5 serene acres of pristine bayfront in Key Largo, Playa Largo Resort & Spa invites you into a realm where elegance meets tranquility. Picture yourself unwinding under swaying palms, the gentle sound of waves lapping at the shore creating a symphony of relaxation as the warm Florida sun bathes you in golden light—a truly idyllic escape for couples and luxury seekers alike.

Romantic Getaway - With private cabanas dotting the beach and fire pits glowing at twilight, every corner of Playa Largo is designed for romance. Enjoy intimate dinners with fresh seafood while the sunset casts a mesmerizing palette across the sky, perfect for creating lasting memories.

Spa Indulgence - At the full-service Ocean Spa, surrender to soothing treatments that rejuvenate both body and soul. Whether you indulge in a blissful massage right in your room or simply bask in the luxurious ambiance, this is a sanctuary where serenity reigns supreme.

Adventurous Escapades - Water sports enthusiasts will find their paradise here, with opportunities for kayaking, paddleboarding, and diving just steps away from your doorstep. Each day promises exciting adventures amidst the vibrant marine life of the Florida Bay—an exhilarating playground waiting to be explored.

Guest Experiences - Imagine sinking your toes into soft sand while sipping on a freshly crafted cocktail, the air perfumed with hints of grilled seafood from the nearby Sol by the Sea restaurant. Guests often rave about the friendly staff who greet you like family, ensuring every moment feels personalized and genuine, even if it means waiting a tad longer to savor that perfect breakfast made just for you.

Nestled on the sun-kissed shores of Marco Island, the JW Marriott Beach Resort stands as a bastion of luxury and serenity. With each wave lapping at the pristine shoreline, this elegant oasis invites you to indulge in a world where your every desire is met with impeccable service and breathtaking views of the Gulf of Mexico.

Total relaxation - Immerse yourself in tranquility at the Spa by JW®, where the air is infused with soothing aromas and the gentle sound of water evokes a sense of calm as skilled therapists work their magic to rejuvenate your body and spirit.

Romantic Break - Bask in the golden glow of sunset from your private balcony, where the vibrant hues of the sky create a picturesque backdrop for intimate evenings spent savoring fine wines and delectable dishes, handpicked from the resort's diverse culinary offerings.

Beach Life - Step onto the soft sands just steps from your door, where the rhythmic lull of the ocean mingles with laughter and the playful splash of families enjoying the outdoor pools—each moment a reminder that paradise is within reach.

Guest Experiences - As you lounge by the pool, the gentle breeze carries the tantalizing scent of grilled seafood, and friendly staff members glide past, ensuring your glass is never empty while the sun dips lower, inviting you to lose track of time amidst the serenity.