The 9 Best Boutique Hotels with Spa in Key Largo (2025)

Nestled in the enchanting Florida Keys, Key Largo is a tropical paradise known for its stunning coral reefs, crystal-clear waters, and vibrant marine life. With a laid-back vibe that embraces both adventure and relaxation, this captivating destination is perfect for sun-soaked getaways filled with outdoor exploration and culinary delights. The boutique hotel scene here reflects the unique charm of the area, offering personalized experiences that elevate every stay. Among the standout options is Bungalows Key Largo - All Inclusive, where guests can revel in luxurious island living with private bungalows and gourmet dining. For those seeking an upscale retreat, Playa Largo Resort & Spa, Autograph Collection offers breathtaking ocean views and a lavish spa experience, providing a true sense of place. Additionally, The Ritz-Carlton Key Biscayne, Miami pairs elegance with coastal beauty, ensuring a refined escape. Whether you’re yearning for adventure or relaxation, explore our collection of Key Largo Boutique Hotels with Spa to discover your perfect getaway and start planning an unforgettable trip.

List Of Best Boutique Hotels with Spa Key Largo

boutique hotels in Key Largo

Bungalows Key Largo - All Inclusive

Resort
99010 Overseas Highway Mile Marker 99 Bayside, Key Largo, FL 33037, USA

Nestled along the pristine shores of Key Largo, Bungalows Key Largo - All Inclusive beckons couples and romantic travelers into a world where luxury meets tranquility. Each luxurious bungalow serves as a private sanctuary, complete with soothing ocean breezes and breathtaking views, ensuring that every moment is tailored for relaxation and intimate connection.

Total Relaxation - Indulge in the serene atmosphere as you bask by the shimmering pools or unwind in your own private hot tub under a starlit sky, where the only sound is the gentle lapping of waves on the shore.

Spa Breaks - Rejuvenate your senses at the full-service spa, where expert therapists blend natural ingredients into treatments designed to melt away stress, leaving you enveloped in tranquility and bliss.

Boutique Beach Life - Discover an exclusive stretch of golden sand where soft towels await, inviting you to sink into plush lounge chairs while sipping on expertly crafted cocktails, all against a backdrop of sapphire waters and swaying palms.

Guest Experiences - As you stroll through the lush grounds, the fragrant aromas of gourmet dishes waft invitingly from the nearby restaurants, mingling with the sounds of laughter from guests savoring sunset sails, capturing the heart of what makes this resort feel like a home away from home.

boutique hotels in Key Largo

Playa Largo Resort & Spa, Autograph Collection

Resort
97450 Overseas Highway, Key Largo, FL 33037, USA

Nestled along 14.5 serene acres of pristine bayfront in Key Largo, Playa Largo Resort & Spa invites you into a realm where elegance meets tranquility. Picture yourself unwinding under swaying palms, the gentle sound of waves lapping at the shore creating a symphony of relaxation as the warm Florida sun bathes you in golden light—a truly idyllic escape for couples and luxury seekers alike.

Romantic Getaway - With private cabanas dotting the beach and fire pits glowing at twilight, every corner of Playa Largo is designed for romance. Enjoy intimate dinners with fresh seafood while the sunset casts a mesmerizing palette across the sky, perfect for creating lasting memories.

Spa Indulgence - At the full-service Ocean Spa, surrender to soothing treatments that rejuvenate both body and soul. Whether you indulge in a blissful massage right in your room or simply bask in the luxurious ambiance, this is a sanctuary where serenity reigns supreme.

Adventurous Escapades - Water sports enthusiasts will find their paradise here, with opportunities for kayaking, paddleboarding, and diving just steps away from your doorstep. Each day promises exciting adventures amidst the vibrant marine life of the Florida Bay—an exhilarating playground waiting to be explored.

Guest Experiences - Imagine sinking your toes into soft sand while sipping on a freshly crafted cocktail, the air perfumed with hints of grilled seafood from the nearby Sol by the Sea restaurant. Guests often rave about the friendly staff who greet you like family, ensuring every moment feels personalized and genuine, even if it means waiting a tad longer to savor that perfect breakfast made just for you.

boutique hotels in Key Largo

The Ritz-Carlton Key Biscayne, Miami

Hotel
455 Grand Bay Drive, Miami, FL 33149, USA

Nestled on a serene five-mile barrier island, The Ritz-Carlton Key Biscayne draws you into its luxurious embrace, where the ocean whispers secrets and palm trees sway in rhythm with your heartbeat. Here, each moment is an invitation to indulge—whether you're seeking romance under the stars or a tranquil escape from the everyday hustle, every detail has been thoughtfully curated for your pleasure.

Romantic Getaway - Immerse yourself in the intimate ambiance of this upscale sanctuary, where stunning ocean views and elegant décor create an enchanting backdrop for couples. Enjoy leisurely strolls along the beach at sunset, hand in hand, as the warm breeze carries the scent of salt and tropical blooms.

Spa & Relaxation - Surrender to tranquility at the expansive 25,000-square-foot spa, where the soothing aroma of eucalyptus fills the air. Experience rejuvenating treatments that leave you feeling blissfully transformed, whether it's basking in the warmth of the hot tubs or unwinding in the Vitamin C-infused showers.

Culinary Delights - Savor the culinary artistry at Lightkeepers, where coastal dishes are elevated with local flavors and presented against a breathtaking oceanfront backdrop. Each bite of expertly crafted cuisine harmonizes with the sound of waves lapping on the shore, making dining a truly immersive experience.

Guest Experiences - As one guest recalls, the delightful ambiance enveloped them as they lounged by the adult pool, sipping a refreshing cocktail while soaking in the serene atmosphere—the gentle rustle of leaves overhead was punctuated by the laughter of friends enjoying their sun-kissed retreat.

boutique hotels in Key Largo

Mr. C Miami - Coconut Grove

Hotel
2988 McFarlane Road, Coconut Grove, Miami, FL 33133, USA

Nestled in the vibrant heart of Coconut Grove, Mr. C Miami exudes a chic elegance that invites you to unwind and indulge. With its stunning views of the Miami skyline and lush garden landscapes, this boutique hotel offers an oasis of luxury where every detail is curated for your comfort and enjoyment.

Chic Retreat - Step into stylishly appointed rooms that blend modern sophistication with classic Italian flair, featuring plush furnishings and tranquil seating areas perfect for quiet reflection or intimate conversations.

Culinary Delights - Savor exquisite dishes at the renowned Bellini restaurant, where the aroma of fresh ingredients fills the air as you relish authentic Italian flavors while dining alfresco against breathtaking vistas.

Wellness Oasis - Rejuvenate your senses at the inviting outdoor pool, where the gentle sounds of water soothe your mind and the sun-drenched terrace beckons for leisurely afternoons spent sipping cocktails amidst lush greenery.

Guest Experiences - As you wander through the art-filled lobby, the warm smiles of the staff greet you like old friends, making even simple moments—like forgetting an earring—transform into cherished memories of attentive care and personal connection.

boutique hotels in Key Largo

Biltmore Hotel Miami Coral Gables

Hotel
1200 Anastasia Avenue, Coral Gables, Miami, FL 33134, USA

Nestled in the heart of Coral Gables, the Biltmore Hotel stands as a timeless sanctuary where historic elegance meets modern luxury. Imposing yet inviting, this iconic resort enchants with its lush landscape and opulent architecture, offering couples and wellness seekers a unique escape just moments from Miami's vibrant pulse.

Romantic Getaway - Embrace intimacy at the Biltmore with romantic dining experiences under a starlit sky, or stroll hand-in-hand through the manicured gardens that whisper secrets of a bygone era. Each luxurious corner beckons you to create lasting memories together.

Spa & Relaxation - Indulge your senses at the full-service spa, where soothing aromas mingle with the gentle sound of water, creating an oasis of peace. Let the skilled therapists whisk you away on a journey of rejuvenation, leaving you floating on clouds after a signature treatment.

Historic Charm - Marvel at the hotel’s stunning architectural details, from the impressive lobby adorned with ornate frescoes to the grand staircase that echoes tales of decades past. The atmosphere is rich with history, captivating guests who appreciate the artistry of a classic era.

Guest Experiences - As you lounge by the expansive pool, enveloped in soft breezes and surrounded by vibrant tropical blooms, you might catch the tantalizing aroma of gourmet cuisine wafting from nearby restaurants, making it hard to resist exploring the culinary offerings just steps away.

boutique hotels in Key Largo

The Ritz-Carlton Coconut Grove, Miami

Hotel
3300 Southwest 27th Avenue, Coconut Grove, Miami, FL 33133, USA

Nestled amidst the lush tropical landscapes of Coconut Grove, The Ritz-Carlton Coconut Grove, Miami, is a sanctuary where elegance meets tranquility. Here, the air is infused with the scent of blooming orchids and sea breezes, enveloping you in an atmosphere of refined luxury and privacy that invites you to escape the ordinary.

Spa Bliss - Indulge your senses at the Ritz-Carlton Spa, where personalized treatments await—imagine the soothing warmth of smooth stones gliding over your back while soft melodies play in the background, lulling you into a state of deep relaxation.

Culinary Delights - Savor light bites and refreshing cocktails at the Poolside Café, where the gentle rustle of palm leaves accompanies your leisurely afternoons, creating a vibrant yet serene dining experience under the sun's warm embrace.

Room with a View - Each spacious suite boasts oversized balconies offering sweeping vistas of Biscayne Bay, allowing you to bask in spectacular sunsets while wrapped in plush robes, the marble finishes echoing the hotel’s sophisticated charm.

Guest Experiences - As you sip your morning coffee on the balcony, you might just catch a glimpse of playful dolphins dancing in the bay below, while the faint sounds of laughter from the pool area remind you of the joy lingering in the air.

boutique hotels in Key Largo

Four Seasons Hotel Miami

Hotel
1435 Brickell Avenue, Brickell, Miami, FL 33131, USA

Nestled above the vibrant pulse of Brickell Avenue, Four Seasons Hotel Miami offers an exquisite blend of lavishness and tranquility. Here, amidst the gleaming skyscrapers and lush tropical gardens, guests are transported into their own serene oasis, where every moment is infused with elegance and a touch of Miami magic.

City Style - Experience the rhythmic heartbeat of Miami as the hotel's elegant architecture and sleek interiors mirror the city's chic flair. Stroll through the lively streets, where upscale boutiques and tantalizing eateries await just moments from your doorstep.

Spa breaks - Indulge in holistic wellness at the spa, where the soothing scent of essential oils fills the air and treatments harness local botanicals for rejuvenation. Each serene massage room invites relaxation, offering a tranquil escape from the dynamic energy of the city.

Swimming Pool - Bask under the warm Miami sun beside the two luxurious outdoor pools, surrounded by swaying palms and inviting cabanas. The shimmering waters reflect the blue sky, while sounds of laughter and gentle splashes create a joyful atmosphere perfect for unwinding.

Guest Experiences - As you sip your morning coffee on your private balcony, the aroma of freshly brewed espresso mingles with the salty breeze from Biscayne Bay, creating a moment that feels like pure bliss. Friendly staff members are quick to share local secrets, making you feel like a cherished part of this vibrant community.

boutique hotels in Key Largo

InterContinental at Doral Miami, an IHG Hotel

Hotel
2505 Northwest 87th Avenue, Doral, Miami, FL 33172, USA

Nestled in the vibrant heart of Doral, the InterContinental at Doral Miami beckons with its sophisticated elegance and modern charm. With lush surroundings that whisper tranquility, this eco-conscious sanctuary is a haven for couples seeking romantic escapes and business travelers craving seamless convenience, all just moments away from the spirited pulse of Miami.

Romantic Escape - Bask in the serene ambiance of the outdoor pool area, where soft whispers of water accompany evening cocktails under twinkling stars, inviting you to unwind and connect with your loved one amidst tropical tranquility.

Gourmet Delights - Savor every moment at Blue Matisse, where the aroma of freshly brewed coffee wafts through the air during decadent breakfast buffets, and the enticing evening menus transform dining into a delightful culinary journey.

Wellness Retreat - Rejuvenate your senses at the 24-hour fitness center, equipped with state-of-the-art machines that overlook lush gardens, creating an invigorating environment that makes your workout feel less like a chore and more like an indulgence.

Guest Experiences - Guests have relished the friendly staff who greet you with warm smiles, ready to whisk you off in the complimentary shuttle to nearby malls, while the pristine rooms, boasting marble bathrooms and soft linens, create a soothing retreat after a bustling day.

boutique hotels in Key Largo

Hotel AKA Brickell

Hotel
1395 Brickell Avenue, Brickell, Miami, FL 33131, USA

Nestled in the vibrant heart of Miami's Business District, Hotel AKA Brickell beckons with its chic elegance and stunning views of Biscayne Bay. Here, modern luxury intertwines seamlessly with a warm, inviting atmosphere, creating an oasis for couples seeking romance, wellness enthusiasts craving tranquility, and adventurous explorers alike.

A Culinary Journey - Savor extraordinary flavors at Adrift Mare, where each meal transforms into an unforgettable experience, from brunches that inspire delight to exquisite dinners paired with curated wines and handcrafted cocktails, all while basking in breathtaking bay views.

Rooftop Retreat - The rooftop pool is not just a place to swim but a serene escape where the sun kisses your skin and gentle breezes rustle through palm fronds—a perfect spot for afternoon lounging or sunset gazing with friends under the Miami sky.

Unmatched Comfort - The spacious rooms exude sophistication, featuring marble bathrooms and plush furnishings that invite guests to unwind; a uniquely comforting aroma fills the air, making it feel like a home away from home, even amid the city's pulse.

Guest Experiences - Imagine waking up to soft sunlight streaming through large windows, the invigorating scent of fresh espresso wafting from your own machine, and the joyous laughter of staff members who feel more like friends, welcoming you back with genuine warmth each time you return.

Best Boutique Hotels with Spa that guests love in Key Largo

boutique hotels in Key Largo
2505 Northwest 87th Avenue, Doral, Miami, FL 33172, United States of America
8.5
813 reviews
From $150

Guest Review: Location friendly staff ,excellent breakfast., club lounge quite small but quality drinks on offer great staff.Also free lift and pick up to mall and restaurants within 3 miles.

boutique hotels in Key Largo
1395 Brickell Avenue, Brickell, Miami, FL 33131, United States
8.4
743 reviews
From $206

Guest Review: The property is located 2 miles from the port of Miami. It was clean and comfortable, and the staff were friendly and professional.

boutique hotels in Key Largo
1200 Anastasia Avenue, Coral Gables, Miami, FL 33134, United States
8.5
586 reviews
From $299

Guest Review: The pool at this hotel is amazing, the grounds are immaculate. The building itself has great architecture. All of the staff were very professional and helpful.

Other great option in Key Largo

boutique hotels in Key Largo
Key Largo, 33037, US
9.8
14 reviews
From $466
boutique hotels in Key Largo
101551 Overseas Highway Lot 110, Key Largo, FL 33037, US
10.0
1 reviews
From $241

Guest Review: The RV was beautiful, fully stocked, nice friendly campground and location was great. We will definitely be going back for another visit here soon.

boutique hotels in Key Largo
97450 Overseas Highway, Key Largo, 33037, US
9.0
1005 reviews
From $323

Key Largo Boutique Hotels on the Map

Frequently Asked Questions

For a luxurious spa experience, consider staying at Playa Largo Resort & Spa, Autograph Collection, renowned for its rejuvenating treatments and serene atmosphere. Another great choice is Bungalows Key Largo - All Inclusive, offering a full-service spa that provides a range of relaxing therapies amidst stunning coastal views.

If you're looking for a romantic getaway, Bungalows Key Largo - All Inclusive features intimate beachfront bungalows perfect for couples. Additionally, Playa Largo Resort & Spa, Autograph Collection offers a beautiful setting with luxury amenities, making it an ideal spot for a romantic retreat.

For a luxurious stay, consider Playa Largo Resort & Spa, Autograph Collection, known for its upscale accommodations and lavish spa services. Another option is Bungalows Key Largo - All Inclusive, which combines luxury with an all-inclusive experience right on the beach.

Families will enjoy Playa Largo Resort & Spa, Autograph Collection, which offers kid-friendly activities alongside an exquisite spa. Another great option is Bungalows Key Largo - All Inclusive, where both adults and children can indulge in relaxation while enjoying all-inclusive amenities in a tropical paradise.

You won't want to miss Playa Largo Resort & Spa, Autograph Collection, situated directly on the beach, featuring a stunning spa and breathtaking ocean views. Also, Bungalows Key Largo - All Inclusive offers direct beach access and a full-service spa, ensuring a perfect blend of relaxation and seaside fun.

While luxury is often the focus, Bungalows Key Largo - All Inclusive offers great value with its all-inclusive package, including spa services that won’t break the bank. This hotel provides both comfort and affordability, making it a fantastic choice for budget-conscious travelers seeking relaxation.