The 4 Best Boutique Hotels with Spa in Indiana (2025)

Step into a world where history meets modern luxury at the Bottleworks Hotel, nestled in the heart of Indianapolis. This beautifully renovated landmark whispers tales of its Art Deco past while inviting you to experience contemporary elegance and upscale comfort, making it the perfect romantic getaway or luxurious retreat for the discerning traveler.

Romantic Break - With intimate ambiance and chic decor that echoes its historic roots, the Bottleworks Hotel sets the stage for unforgettable moments. Stroll hand-in-hand along Massachusetts Avenue, then return to unwind in your spacious sanctuary, where plush bedding and sumptuous showers await.

Boutique - Each corner of the hotel is adorned with curated artwork and playful design elements, offering a sensory feast that invites exploration. Whether it's the bubbling water fountains or the intricate details of the original architecture, this boutique gem transports you to a realm of artistic inspiration.

Spa breaks - Indulge in self-care at the on-site spa, where serenity envelops you in soothing scents and tranquil sounds. After a rejuvenating treatment, retreat to the serene terrace and bask in the gentle Indiana breeze as you sip on a craft cocktail.

Guest Experiences - Upon entering the hotel, the air carries a delightful mix of fresh coffee and subtle floral notes from the nearby fountains. One guest marveled at their spacious room, declaring the bed 'super comfy' while reminiscing about the warmth of the staff—especially Renee, whose genuine concern helped reunite them with their forgotten bag, turning a routine check-in into an incredibly personal experience.

Nestled in the vibrant heart of Indianapolis’ north side, Ironworks Hotel Indy is more than a boutique stay; it’s a romantic retreat where modern elegance meets rustic charm. With its tantalizing aromas wafting from upscale dining and an inviting rooftop lounge that beckons couples to unwind beneath starry skies, this hotel promises a luxurious yet intimate escape for discerning travelers.

Chic Accommodations - Every room at Ironworks balances sophisticated rustic décor with contemporary comforts, featuring plush bedding and walk-in showers framed by frosted glass—an indulgent treat for couples seeking seclusion and style.

Culinary Discoveries - Savor craft cocktails and exquisite dishes at Provisions, where the bartenders greet you with genuine warmth as you sip drinks infused with local flavors, setting the stage for memorable evenings filled with laughter and connection.

Wellness & Relaxation - The sleek fitness center invites guests to maintain their routines, while the serene atmosphere throughout the hotel encourages moments of quiet reflection—perfect for wellness enthusiasts looking to recharge amidst urban excitement.

Guest Experiences - Guests often speak fondly of the delightful scent that greets them upon entering, reminiscent of rich coffee and artisanal pastries, creating a warm ambiance that feels like home. The enchanting raindrop shower has become a highlight, providing a soothing experience that guests can't stop raving about, making each moment spent there feel refreshingly special.

Nestled in the vibrant heart of downtown Indianapolis, Conrad Indianapolis offers a sanctuary of refined elegance and modern design. With its chic atmosphere, breathtaking art adorning every corner, and the soft glow of ambient lighting, this upscale retreat invites couples and luxury seekers alike to indulge in an exquisite escape.

Total Relaxation - Unwind at the on-site Conrad Spa, where curated treatments envelop you in tranquility, leaving you rejuvenated and glowing. Each treatment is executed with finesse, ensuring that your visit feels like a personalized journey toward complete wellness.

Outstanding Location - Perfectly positioned along the Indianapolis Cultural Trail, you’re just steps away from iconic sights like Monument Circle and the dynamic Indiana Convention Center. The city’s vibrant energy surrounds you, offering the perfect backdrop for leisurely strolls or spirited cultural explorations.

Chic Hotel Entertainment - The Lounge provides a sophisticated yet inviting atmosphere, where the clink of wine glasses complements the gentle hum of conversation. Guests relish in the curated selection of drinks while soaking up the exquisite decor, which transforms the lobby into a gallery of modern artistry.

Guest Experiences - Picture yourself wrapped in plush bathrobes, slipping into the marbled bathroom where a luxurious TV mirror reflects your contentment. Guests often reminisce about the delightful smell of fresh coffee wafting through the halls each morning, paired with the sound of welcoming greetings from the friendly staff, making every moment feel special.

Nestled in the heart of downtown Louisville, the 21c Museum Hotel seamlessly blends contemporary art with luxurious accommodations, crafting an enchanting retreat for couples and cultural explorers alike. As you step into this vibrant space, the air is infused with a sense of creativity, inviting you to indulge in both relaxation and artistic inspiration.

Artworks & Culture - Immerse yourself in a dynamic fusion of art and hospitality, where each corner reveals thought-provoking installations that spark conversation and ignite your imagination.

Outstanding Location - Ideally situated just steps away from the city's iconic attractions, venture out to discover the rich history of Louisville or savor the local culinary scene without ever needing to stray far from your elegant oasis.

Spa & Wellness - Unwind in the tranquil spa, where soothing scents of essential oils mingle with soft music, providing an escape from the hustle and bustle of city life while rejuvenating your body and spirit.

Guest Experiences - Guests often recount the moment they first entered their spacious room, greeted by plush bedding and the subtle scent of fresh lavender; it's a cozy haven that makes you feel instantly at home, complemented by the friendly staff who remember your name as if you were family.