The 9 Best Boutique Hotels with Spa in Brussels Region (2025)

Nestled at the heart of Europe, the Brussels Region enchants with its blend of medieval charm and modern vibrancy. From the stunning Gothic architecture of the Grand Place to the tantalizing aroma of freshly made waffles wafting through cobblestone streets, this city pulses with a unique cultural rhythm. As you explore, the allure of boutique hotels awaits, each offering an intimate glimpse into the rich tapestry of local life. For instance, the Juliana Hotel Brussels boasts a sophisticated design that combines elegance with contemporary flair, positioning it as an oasis in the bustling city center. Just a stone's throw away, Hotel Manos Premier captivates guests with its Art Deco style and lush gardens, providing a serene retreat after a day of exploration. Meanwhile, YOOMA Urban Lodge embodies a playful spirit with its eclectic decor and focus on community, perfect for adventurous travellers. Embrace the charm of the Brussels Region boutique hotels with spa offerings, where personalized service transforms your stay into an unforgettable experience. Let our collection inspire your next getaway!

List Of Best Boutique Hotels with Spa Brussels Region

boutique hotels in Brussels Region

Juliana Hotel Brussels

Hotel
4 Place des Martyrs, 1000 Brussels, Belgium

Nestled in the heart of Brussels, Juliana Hotel & Spa offers an enchanting blend of elegance and modern luxury. Here, every corner invites you to unwind— from the plush interiors that whisper of romance to the soothing sounds of the spa’s tranquil ambiance, creating a perfect haven for couples and cultural explorers alike.

Spa Retreat - Immerse yourself in serenity at the hotel’s wellness sanctuary, where the delicate aroma of essential oils mingles with soft music, transporting you to a realm of relaxation. The Turkish bath beckons with promises of rejuvenation, while the indoor pool glimmers invitingly under ambient lighting.

Culinary Delights - Savor exquisite culinary creations in the hotel's chic restaurant, where the enticing scent of freshly prepared dishes lingers in the air. Start your day with a sumptuous breakfast spread or indulge in evening cocktails crafted to perfection, each sip enhancing the cozy yet sophisticated atmosphere.

Outstanding Location - Situated just a short stroll from the iconic Belgian Comic Strip Center, the hotel places you within reach of Brussels' vibrant culture. Picture wandering through historic streets lined with artistic treasures, then returning to the blissful sanctuary of your luxurious room, offering an oasis amidst the city's buzz.

Guest Experiences - Imagine settling into a junior suite after a day of exploration, enveloped by the soft embrace of high-thread-count sheets. Guests have shared whispers of how the attentive staff anticipates needs without being intrusive, leaving just enough warmth in their friendly smiles to make you feel right at home.

boutique hotels in Brussels Region

Hotel Manos Premier

Hotel
Chaussée de Charleroi 100-106, Sint-Gillis / Saint-Gilles, 1060 Brussels, Belgium

Nestled in a quiet enclave just moments away from the vibrant Avenue Louise, Hotel Manos Premier exudes an air of exclusive sophistication that feels like a well-kept secret. Upon entering, guests are enveloped by a regal ambiance, where every corner whispers tales of luxury and charm reminiscent of a grand private residence. This boutique hotel is a sanctuary for those seeking intimate elegance and rejuvenation amidst the bustling heart of Brussels.

Total Relaxation - Indulge in a spa experience that transcends the ordinary, featuring mosaic-tiled steam baths and soothing hot tubs, each designed to transport you to a realm of tranquility. The serene garden, lush and inviting, offers a perfect backdrop for relaxation while listening to the gentle sound of water cascading from the fountain.

Romantic Break - With its antique Louis XV and XVI furnishings, each uniquely curated room invites couples to immerse themselves in romance. Softly scented linens and plush pillows create an oasis of comfort, perfect for intimate evenings spent reflecting on the day’s adventures in this enchanting city.

Cultural Explorers - Located within walking distance of Brussels’ historical sights, Hotel Manos Premier serves as an ideal base for cultural exploration. Stroll through charming neighborhoods, savor local delicacies at nearby markets, and return to the hotel’s elegant atmosphere, where each detail resonates with the essence of Belgium's rich heritage.

Guest Experiences - Guests have shared delightful moments of coziness as they sank into their sumptuous beds, wrapped in the fragrance of freshly laundered towels infused with delicate scents. The attentive staff, always ready with a warm smile, made even the simplest requests feel special—a small gesture that turned everyday experiences into lasting memories.

boutique hotels in Brussels Region

YOOMA Urban Lodge

Hotel
Square De L'aviation 23-27, Anderlecht, 1070 Brussels, Belgium

Nestled in the heart of Brussels, YOOMA Urban Lodge is a whimsical retreat where Franco-Belgian comic artistry meets modern luxury. Its playful yet elegant atmosphere draws in couples and adventurous travelers eager to explore the city while indulging in serene relaxation and comfort.

Romantic Getaway - Surrounded by vibrant comic book themes, each room at YOOMA is a cozy escape that invites guests to experience the magic of storytelling with every stay. The intimate ambiance sets the stage for romantic evenings, whether lounging on your private terrace or enjoying a candlelit dinner curated from locally inspired flavors.

Total Relaxation - Unwind in the soothing wellness area featuring a hammam and sauna, where soft aromas mingle and envelop you in tranquility. The rooftop lounge beckons with comfortable seating under the stars, perfect for starlit conversations or peaceful moments with a good book.

Cultural Explorers - Immerse yourself in the lively culture of Brussels as you wander through nearby local markets and historic sights, all within walking distance. Enjoy the thrill of discovering the charming neighborhoods before retreating to this artistic haven that feels like stepping into a comic strip.

Guest Experiences - One guest recounted the delightful surprise of finding their room adorned with playful comic decorations, instantly igniting joy and nostalgia. Laughter echoed from the basement arcade, where families shared light-hearted competition over games, enhancing the hotel’s inviting, communal spirit.

boutique hotels in Brussels Region

Sofitel Brussels Europe

Hotel
Place Jourdan 1, Etterbeek, 1040 Brussels, Belgium

Nestled on the vibrant Place Jourdan, Sofitel Brussels Europe invites you into a world of elegance and romance. With stylish interiors that embody the essence of contemporary luxury, this 5-star haven is just moments away from the heart of Europe's political landscape and the historical charm of Brussels, creating an alluring atmosphere for both leisure and business travelers alike.

Total relaxation - Indulge in rejuvenation at the serene hammam, where the soothing aroma of warm steam envelops you, setting the stage for a blissful escape from the city's hustle and bustle.

Romantic Break - The intimate ambiance of the chic bar offers a perfect backdrop for couples to sip on expertly crafted cocktails, accentuated by the delightful hum of conversation and laughter that fills the air as twilight descends.

Foodies - Savor exquisite Belgian dishes at the 1040 restaurant, where each bite is a celebration of local flavors, expertly reimagined with fresh, seasonal ingredients that evoke both nostalgia and innovation on your palate.

Guest Experiences - As you enter your room, the inviting scent of Balmain toiletries wafts through the air, while the plush bathrobe hanging in the spacious bathroom promises cozy evenings after a long day of exploring. A helpful staff member even presented an exercise mat upon request, adding a thoughtful touch that made your stay feel personal and well-catered.

boutique hotels in Brussels Region

The Hotel Brussels

Hotel
Boulevard De Waterloo 38, 1000 Brussels, Belgium

Perched high above the vibrant streets of Brussels, The Hotel Brussels unfolds like a luxurious retreat in the sky. With breathtaking panoramic views that stretch across the cityscape and an atmosphere steeped in elegance, guests are invited to indulge in a world where chic sophistication meets intimate comfort.

Spa & Relaxation - Discover serenity at the Urban Spa by CODAGE, where the gentle aroma of essential oils wafts through the air as you unwind in saunas and treatment rooms with sweeping views over the city. Each moment here invites you to escape and rejuvenate, making it a haven for wellness enthusiasts.

Outstanding Location - Situated a mere stone's throw from the pulse of Avenue Louise and the cultural gems of Brussels, The Hotel ensures you’re never far from designer boutiques and art-filled museums. The Louise Metro Stop, just steps away, offers seamless access to explore the city's many treasures.

Chic Dining Experience - Indulge your culinary senses at The Iris, where each meal is a celebration of fresh, local ingredients crafted into artful dishes. The lively buzz of the bar complements the gastronomic experience, making it a perfect spot for romantic dinners or lively gatherings with friends.

Guest Experiences - One guest fondly remembers the delightful surprise of complimentary snacks and drinks awaiting them in their room after a long day of exploring—an unexpected touch that made their stay feel extra special. The soothing sound of laughter from the spa area floated into their room, hinting at the relaxation that awaited just beyond their door.

boutique hotels in Brussels Region

Steigenberger Icon Wiltcher's

Hotel
Avenue Louise 71, 1050 Brussels, Belgium

Nestled in the heart of Brussels, Steigenberger Icon Wiltcher's invites you to experience a harmonious blend of luxury and intimacy. Here, the elegance of modern design meets timeless charm, enveloping guests in a serene atmosphere that whispers romance and sophistication at every turn.

Total Relaxation - Unwind in the opulent spa, where the soothing aromas of essential oils and the gentle sound of water create an oasis of calm, ideal for wellness enthusiasts seeking rejuvenation after a day of exploring the city's vibrant streets.

Outstanding Location - Situated near Porte Louise, this architectural gem offers easy access to chic boutiques, artistic treasures, and the historic Sablon square, making it a perfect base for cultural explorers eager to delve into Brussels’ rich heritage.

Culinary Delights - Indulge in a culinary journey at Loui restaurant, where the delightful aroma of fresh ingredients wafts through the air as the skilled chefs prepare both traditional and contemporary dishes, ensuring each meal is a memorable celebration of flavors.

Guest Experiences - As a guest settled into their spacious room, they marveled at the plush bedding and the luxurious bathroom, complete with a big bathtub; the delightful breakfast buffet was an inviting array of warm pastries and savory options, leaving them impressed with the attentive staff who remembered their coffee preferences.

boutique hotels in Brussels Region

Aspria Royal La Rasante Hotel & Spa

Hotel
Rue Sombre 56, Sint-Lambrechts-Woluwe / Woluwe-Saint-Lambert, 1200 Brussels, Belgium

Nestled in the tranquil embrace of Brussels, Aspria Royal La Rasante Hotel & Spa exudes an air of refined elegance and intimate charm. With its chic interiors and lush green surroundings, this upscale retreat offers a unique sanctuary for couples, wellness seekers, and cultural explorers alike, inviting you to unwind in style while savoring the best of Belgian hospitality.

Total relaxation - Indulge in a blissful escape at the hotel's expansive spa and wellness center, where the soothing sounds of water mingle with gentle aromas of essential oils, creating an atmosphere that whispers tranquility.

Romantic Break - Share a romantic evening on the terrace, sipping handcrafted cocktails under a canopy of stars, as the soft rustle of leaves and distant laughter set the perfect backdrop for cherished moments together.

Great walks - Venture into the nearby verdant gardens, where the crisp morning air is perfumed with blooming flowers, making each stroll a delightful exploration of nature's beauty just steps from your door.

Guest Experiences - One guest fondly recalled the serene ambiance of the spa, where they were enveloped by the warmth of well-designed saunas and the scent of calming herbs, wishing they could linger longer in such peacefulness. Another shared how the attentive staff went out of their way to ensure their breakfast table was adorned with fresh pastries and aromatic coffee, making every morning feel like a special occasion.

boutique hotels in Brussels Region

Pullman Brussels Centre Midi

Hotel
Place Victor Horta 1, Sint-Gillis / Saint-Gilles, 1060 Brussels, Belgium

Nestled in the heart of Brussels, directly connected to the vibrant Gare du Midi, Pullman Brussels Centre Midi envelops you in a world of modern luxury and effortless charm. With a harmonious blend of sophisticated decor and intimate ambiance, this hotel serves as a romantic escape for couples and a welcoming haven for travelers seeking adventure in Belgium's capital city.

Culinary Delights - Indulge in a culinary journey at the Victor Bar & Restaurant, where European flavors intertwine with contemporary twists, ensuring every meal is a delightful experience. The rustic scents of freshly prepared dishes waft through the air, inviting food lovers to savor each bite.

Wellness Retreat - Rejuvenate your spirit in the tranquil spa, featuring a sauna that radiates warmth and relaxation. Here, the gentle sounds of soft music create an oasis of calm, perfect for unwinding after a day spent exploring the city.

Unbeatable Convenience - Boasting direct access to Gare du Midi, the hotel offers unparalleled convenience for those arriving by train. The ease of slipping into your room without ever stepping outside is a luxurious perk, especially cherished during chilly winter evenings.

Guest Experiences - Guests find solace in the beautifully designed rooms, where the comfort of plush bedding meets stunning city views. One traveler mentioned how the quiet hum of the city faded away once the windows were closed, leaving only the soothing sound of a rain shower in the elegantly appointed bathroom.

boutique hotels in Brussels Region

Martin's Château Du Lac

Hotel
Avenue du Lac 87, 1332 Genval, Belgium

Nestled between the tranquil waters of Genval Lake and lush, manicured gardens, Martin's Château Du Lac envelops you in a rare blend of historical elegance and modern luxury. This century-old chateau invites romantic escapades, rejuvenating retreats, and cherished memories, all while whispering tales of serene indulgence and upscale comfort.

Romantic Break - Experience intimate moments as you stroll hand-in-hand through the enchanting landscaped park, the gentle rustle of leaves and the soft lapping of lake water creating a symphony just for you.

Spa breaks - Delight in a sanctuary of calm where the scent of essential oils mingles with soothing melodies; indulge in bespoke treatments that elevate your senses, from revitalizing massages to tranquil bubble baths that whisk you away from the everyday grind.

Great walks - Take in the fresh, crisp air on picturesque trails that weave through the serene surroundings, where every turn reveals stunning vistas and secret spots perfect for quiet reflection or spirited adventure.

Guest Experiences - Imagine waking up to the aroma of a sumptuous breakfast buffet, where the sight of steaming pastries and fresh fruits beckon you to linger awhile longer, or perhaps enjoying a drink at the Kingfisher bar, where the laughter of other guests blends harmoniously with the clinking of glasses, making every sip a celebration.

Best Boutique Hotels with Spa that guests love in Brussels Region

boutique hotels in Brussels Region
Boulevard De Waterloo 38, 1000 Brussels, Belgium
8.7
9569 reviews
From $175

Guest Review: Great location, amazing hotel, loved the spa area, would recommend it, worth the money.

boutique hotels in Brussels Region
Place Victor Horta 1, Sint-Gillis / Saint-Gilles, 1060 Brussels, Belgium
8.3
3865 reviews
From $133

Guest Review: The proximity to the Bruxelles Midi station can't be beat. To have access to the hotel from inside the train station is next level, especially, during the cold winter months. The staff was very,friendly and check-out was a breeze, with the Key Drop option. The room was beautifully decorated, clean and provided the amenities needed for one night, or several nights.

boutique hotels in Brussels Region
Square De L'aviation 23-27, Anderlecht, 1070 Brussels, Belgium
8.6
2922 reviews
From $150

Guest Review: Excellent service from the staff, good amenities, modern and different style and design, very cool!!

Brussels Region Boutique Hotels on the Map

Frequently Asked Questions

For a relaxing escape, consider Aspria Royal La Rasante Hotel & Spa, known for its comprehensive wellness offerings. Another great option is Sofitel Brussels Europe, which features a luxurious spa experience, perfect for unwinding after a day of sightseeing.

Yes! For a romantic getaway, check out Hotel Manos Premier with its intimate ambiance and charming decor. Additionally, The Hotel Brussels offers stunning city views and a sophisticated atmosphere, ideal for couples seeking a memorable stay.

If you're looking for luxury, Steigenberger Icon Wiltcher's provides opulent accommodations along with exquisite dining options. Alternatively, Sofitel Brussels Europe combines modern elegance with world-class service, making it a standout choice in the Brussels Region.

For family-friendly stays, YOOMA Urban Lodge offers spacious rooms designed for comfort and fun. Additionally, Martin's Château Du Lac boasts great amenities for kids and beautiful surroundings for family activities.

Absolutely! Juliana Hotel Brussels showcases contemporary design with a chic vibe, while The Hotel Brussels features stylish interiors and panoramic views of the city, making them both perfect choices for design lovers.

For travelers on a budget, Pullman Brussels Centre Midi offers modern accommodations at reasonable prices. Another excellent option is YOOMA Urban Lodge, known for its affordability without compromising on style or comfort.

For impressive views, The Hotel Brussels features rooms with breathtaking panoramas of the city skyline. Similarly, Sofitel Brussels Europe offers stunning vistas from its higher floors, providing an unforgettable backdrop during your stay.