The 20 Best Boutique Hotels in Florida Keys (2026)

For a romantic escape, consider Alexander's Gay Lesbian Guesthouse (Adult Only 21+), known for its intimate atmosphere and welcoming vibe. Another option is The Mermaid & The Alligator, where stunning gardens and cozy rooms create a perfect romantic retreat.

Food enthusiasts will love Santa Maria Suites Resort, featuring an on-site restaurant that offers delicious local cuisine. Additionally, The Perry Hotel & Marina Key West boasts culinary experiences paired with fresh seafood and craft cocktails, perfect for savoring the flavors of the Keys.

If you’re looking for great value, check out Truman Hotel, which offers comfortable accommodations without breaking the bank. Another excellent choice for budget-conscious travelers is Coconut Palm Inn, where you can enjoy beachfront views at an affordable price.

Indulge in opulence at Bungalows Key Largo - All Inclusive, an all-inclusive resort offering upscale amenities and services. Alternatively, H2O Suites- Adults Only provides a chic, luxurious experience with modern suites and personalized service for guests seeking sophistication and comfort.

Families will appreciate Andrews Inn & Garden Cottages, featuring spacious cottages and a family-friendly environment. Additionally, Largo Resort offers a relaxing atmosphere with kid-friendly amenities, making it a great choice for a memorable family vacation.

For breathtaking views, stay at Orchid Key Inn - Adults Only, where you can admire sunset scenery from your private balcony. Another excellent option is Key West Harbor Inn - Adults Only, offering picturesque waterfront views and a serene atmosphere for a relaxing getaway.